Chemical Property of Furagin
Chemical Property:
- Melting Point:267-270oC (dec.)
- Refractive Index:1.689
- PKA:7.79±0.10(Predicted)
- PSA：120.73000
- Density:1.61 g/cm3
- LogP:1.52850
- Storage Temp.:Refrigerator
- XLogP3:0.5
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:3
- Exact Mass:264.04946937
- Heavy Atom Count:19
- Complexity:455
- Purity/Quality:
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99%, *data from raw suppliers
Furagin *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:C1C(=O)NC(=O)N1N=CC=CC2=CC=C(O2)[N+](=O)[O-]
- Isomeric SMILES:C1C(=O)NC(=O)N1/N=C/C=C/C2=CC=C(O2)[N+](=O)[O-]
- Recent EU Clinical Trials:A Phase II, Randomized, Parallel design, Open label, Dose ranging Study to evaluate the efficacy and safety of Furazidin vaginal tablets in women with bacterial vaginosis
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Description
Furagin (Furazidine) is a Nitrofuran derivative with anti-infective activity used for urinary tract infections. It's chemical structure and composition are similar to Nitrofurantoin.
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Uses and Mechanism of Action
Furagin is used in the management of urinary tract infections caused by susceptible bacteria.
Works by inhibiting bacterial growth and replication, thereby resolving the infection.
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Sources
Synthetically manufactured in pharmaceutical laboratories.
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References
[1] The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors
DOI 10.1080/14756366.2020.1752201
[2] Clinical trial research on furagin-induced anaphylactic shock: assessing mechanisms and preventive strategies
DOI 10.22141/2224-0586.19.7.2023.1632
