6301-02-6

Basic information

• Product Name: 1-AMINOHYDANTOIN
• Synonyms: 1-AMINOHYDANTOIN;1-AMINO-IMIDAZOLIDINE-2,4-DIONE
• CAS NO: 6301-02-6
• Molecular Formula: C₃H₅N₃O₂
• Molecular Weight: 115.09
• EINECS: 228-593-3
• Mol File: 6301-02-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 195-196 °C
• Appearance: /
• Density: 1.506 g/cm³
• Refractive Index: 1.556
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 7.88±0.10(Predicted)
• CAS DataBase Reference: 1-AMINOHYDANTOIN(CAS DataBase Reference)
• NIST Chemistry Reference: 1-AMINOHYDANTOIN(6301-02-6)
• EPA Substance Registry System: 1-AMINOHYDANTOIN(6301-02-6)

Safety Data

• Hazardous Substances Data: 6301-02-6(Hazardous Substances Data)

Usage

General Description

1-Aminohydantoin, also known as glycouril or acylhydantoin, is a chemical compound that contains both an amino group and a hydantoin functional group. It is an intermediate in the synthesis of the common sweetening agent, sucralose, and is used as a precursor for the production of various drugs and agrochemicals. 1-Aminohydantoin is also a known mutagen and has been used in studies to assess its genetic toxicity. Its chemical structure and properties make it a versatile building block for the creation of various organic compounds.

InChI:InChI=1/C3H5N3O2/c4-6-1-2(7)5-3(6)8/h1,4H2,(H,5,7,8)

Upstream product

• 138-07-8 2-semicarbazide acetic acid 
• 590-28-3 potassium cyanate 
• 6945-92-2 2-hydrazinyl acetic acid ethyl ester hydrochloride 
• 67-20-9 Nitrofurantoin 

Downstream Products

• 101655-00-9 1-(4-ethanesulfonyl-benzylidenamino)-imidazolidine-2,4-dione 
• 67-20-9 Nitrofurantoin 
• 17577-67-2 1-(4-nitro-benzylideneamino)-imidazolidine-2,4-dione 
• 92290-13-6 1-(4-methoxy-benzylideneamino)-imidazolidine-2,4-dione 
• 99973-27-0 4-[(2,4-dioxo-imidazolidin-1-ylimino)-methyl]-benzoic acid 
• 1672-88-4 1-{[(1E,2E)-3-(5-nitrofuran-2-yl)prop-2-ene-1-ylidene]amino}imidazolidin-2,4-dione 
• 833480-90-3 dantrolene 

Relevant articles and documents

Photolytic and photocatalytic degradation of nitrofurantoin and its photohydrolytic products

TiO2 based photocatalytic degradation of nitrofurantion (NFT), a widely used drug, and its primary decomposition products, nitrofuraldehyde (NFA) and aminohydantoin (AHD) was investigated and compared to their photolysis in aerobic systems. UV–vis spectrophotometry, pH, IC, and HPLC measurements were applied to follow the changes during the irradiations and subsequently, in the dark. After a fast anti→syn (or trans→cis) photoisomerization of NFT (giving i-NFT), a slower photohydrolysis of both isomers took place upon UV excitation, leading to the formation of NFA and AHD. i-NFT proved to be more reactive than NFT; it underwent hydrolysis in the dark, too. While photolysis could not totally convert NFT and i-NFT within 120 min, they disappeared within 90 min during the photocatalysis under the same irradiation conditions, along with the degradation of NFA and AHD, and the accumulation of a rather stable intermediate identified as 5-hydroxyfuran-2-carbaldehyde, formed from NFA. The direct photolysis of NFA also gave this characteristic intermediate along with its several derivatives formed via addition or condensation then redox transformations. They very slowly decomposed in photolysis, while totally disappeared during photocatalysis of NFA, producing polar aliphatic intermediates. Direct irradiation could not convert AHD, while photocatalysis led to its significant degradation in aerobic system. These results indicate that TiO2 based photocatalysis is suitable for the efficient decomposition of NFT and their photoderivatives.

PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS

The invention relates to a process for straightening keratin fibres, comprising: (i) a step in which a straightening composition containing at least two denaturing agents is applied to the keratin fibres, (ii) a step in which the temperature of the keratin fibres is raised, using a heating means, to a temperature of between 110 and 250° C.