2-(Pyrrolidin-1-yl)butanenitrile

Base Information

Chemical Name:2-(Pyrrolidin-1-yl)butanenitrile
CAS No.:65282-23-7
Molecular Formula:C8H14N2
Molecular Weight:138.213
Hs Code.:
European Community (EC) Number:970-633-3
Nikkaji Number:J2.193.022I
Mol file:65282-23-7.mol

Synonyms:2-(pyrrolidin-1-yl)butanenitrile;65282-23-7;2-pyrrolidin-1-ylbutanenitrile;SCHEMBL443538;|A-Ethyl-1-pyrrolidineacetonitrile;AKOS009986205;CS-0253103;EN300-624318

Suppliers and Price of 2-(Pyrrolidin-1-yl)butanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
a-ethyl-1-Pyrrolidineacetonitrile 97.00%
25G
$ 4010.00

AccelPharmtech
a-ethyl-1-Pyrrolidineacetonitrile 97.00%
5G
$ 2180.00

AccelPharmtech
a-ethyl-1-Pyrrolidineacetonitrile 97.00%
1G
$ 1940.00

Total 4 raw suppliers

Chemical Property of 2-(Pyrrolidin-1-yl)butanenitrile

Chemical Property:

Boiling Point:90 - 92 °C (15 mmHg)
PSA：27.03000
LogP:1.32228
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:138.115698455
Heavy Atom Count:10
Complexity:139

Purity/Quality:

99% ^*data from raw suppliers

a-ethyl-1-Pyrrolidineacetonitrile 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C#N)N1CCCC1

Technology Process of 2-(Pyrrolidin-1-yl)butanenitrile

There total 2 articles about 2-(Pyrrolidin-1-yl)butanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 123-75-1
pyrrolidine

: potassium cyanide

: 123-38-6
propionaldehyde

: 65282-23-7
2-(pyrrolidine-1-yl)butanenitrile

Guidance literature:: propionaldehyde; With sodium hydrogensulfite; In methanol; water; for 2h;

pyrrolidine; potassium cyanide; In methanol; water; for 16h;

Reference yield:

: 25150-61-2
pyrrolidine hydrochloride

: 123-38-6
propionaldehyde

: 65282-23-7
2-(pyrrolidine-1-yl)butanenitrile

Guidance literature:

Reference yield:

: 65282-23-7
2-(pyrrolidine-1-yl)butanenitrile

: 102767-28-2
levetiracetam

Guidance literature:: Multi-step reaction with 2 steps

1: nitrile hydratase from Comamonas testosteroni; water / 2 h / 25 °C / pH 7 / Resolution of racemate; Enzymatic reaction

2: sodium periodate; (x)H₂O*O₄Ru / ethyl acetate / 0.5 h / 20 °C / Electrochemical reaction

With sodium periodate; (x)H₂O*O₄Ru; water; nitrile hydratase from Comamonas testosteroni; In ethyl acetate;
DOI:10.1039/d0gc03358h