4-[(4-Dimethylamino-benzylidene)-amino]-phenol

Base Information

• Chemical Name: 4-[(4-Dimethylamino-benzylidene)-amino]-phenol
• CAS No.: 3230-38-4
• Molecular Formula: C15H16N2O
• Molecular Weight: 240.305
• European Community (EC) Number: 667-312-2
• NSC Number: 112119
• DSSTox Substance ID: DTXSID80296843
• Nikkaji Number: J2.000.068F
• ChEMBL ID: CHEMBL2236146
• Mol file: 3230-38-4.mol

Synonyms:3230-38-4;4-[(4-Dimethylamino-benzylidene)-amino]-phenol;NSC112119;Oprea1_100278;Oprea1_485357;CHEMBL2236146;SCHEMBL11007314;DTXSID80296843;STK046905;AKOS000487696;NSC-112119;NCGC00327289-01;AB01321956-02;SR-01000311163;4-(4-(DIMETHYLAMINO)BENZYLIDENEAMINO)PHENOL;SR-01000311163-1;4-({(E)-[4-(dimethylamino)phenyl]methylidene}amino)phenol;4-[(e)-{[4-(dimethylamino)phenyl]methyliden}amino]phenol

Chemical Property of 4-[(4-Dimethylamino-benzylidene)-amino]-phenol

Chemical Property:

• Vapor Pressure: 5E-08mmHg at 25°C
• Boiling Point: 430.8°Cat760mmHg
• Flash Point: 214.4°C
• Density: 1.05g/cm³
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 240.126263138
• Heavy Atom Count: 18
• Complexity: 262

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)C=NC2=CC=C(C=C2)O

Technology Process of 4-[(4-Dimethylamino-benzylidene)-amino]-phenol

There total 2 articles about 4-[(4-Dimethylamino-benzylidene)-amino]-phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4-amino-phenol (123-30-8) + 4-dimethylamino-benzaldehyde (100-10-7) → p-dimethylaminobenzaldehyde adduct of 4-aminophenol (3230-38-4,193892-32-9)

Guidance literature:

In neat(no solvent); at 110 ℃; for 0.0166667h; Microwave irradiation;

DOI:10.1002/jhet.604

Reference yield:

→ p-dimethylaminobenzaldehyde adduct of 4-aminophenol (3230-38-4,193892-32-9)

Guidance literature:

/BRN= 3302780/;

Reference yield: 91.0%

p-dimethylaminobenzaldehyde adduct of 4-aminophenol (3230-38-4,193892-32-9) + benzil (134-81-6) → C29H25N3O (1233762-73-6)

Guidance literature:

With ammonium acetate; silica gel; for 0.3h; Microwave irradiation; neat (no solvent);

upstream raw materials:

4-amino-phenol

4-dimethylamino-benzaldehyde

Downstream raw materials:

Pd₂(OCOCH₃)2(HOC₆H₄NCHC₆H₃N(CH₃)2)2

4-[2-(4-dimethylaminophenyl)imidazo[4,5-b]indol-3(4H)-yl]phenol

C₂₉H₂₅N₃O

Pd(HOC₆H₄NCHC₆H₃N(CH₃)2)(HOC₆H₄NCHC₆H₃ONO₂)