2,8-Decadiene-4,6-diynedioic acid, dimethyl ester, (E,Z)-

Base Information

• Chemical Name: 2,8-Decadiene-4,6-diynedioic acid, dimethyl ester, (E,Z)-
• CAS No.: 65367-63-7
• Molecular Formula: C12H10O4
• Mol file: 65367-63-7.mol

Synonyms:

Chemical Property of 2,8-Decadiene-4,6-diynedioic acid, dimethyl ester, (E,Z)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,8-Decadiene-4,6-diynedioic acid, dimethyl ester, (E,Z)-

There total 2 articles about 2,8-Decadiene-4,6-diynedioic acid, dimethyl ester, (E,Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl (triphenylphosphoranylidene)acetate (21204-67-1,2605-67-6) + Hexa-2,4-diyne-1,6-diol (3031-68-3) → deca-2t,8t-diene-4,6-diynedioic acid dimethyl ester (54981-67-8) + (2E,8Z)-deca-2,8-diene-4,6-diynedioic acid dimethyl ester (65367-63-7)

Guidance literature:

With Dess-Martin periodane; benzoic acid; In dichloromethane; dimethyl sulfoxide; for 0.5h; Yield given. Yields of byproduct given; Ambient temperature;

DOI:10.1021/jo971569u

Reference yield:

(E)-5-pent-2-en-4-ynoic acid methyl ester (41345-43-1) + (Z)-5-iodopent-2-en-4-ynoic acid methyl ester (1192834-84-6) → deca-2t,8t-diene-4,6-diynedioic acid dimethyl ester (54981-67-8) + (2E,8Z)-deca-2,8-diene-4,6-diynedioic acid dimethyl ester (65367-63-7) + (2Z,8Z)-deca-2,8-diene-4,6-diynedioic acid dimethyl ester (1192834-89-1)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2009.07.082

upstream raw materials:

methyl (triphenylphosphoranylidene)acetate

Hexa-2,4-diyne-1,6-diol

(E)-5-pent-2-en-4-ynoic acid methyl ester

(Z)-5-iodopent-2-en-4-ynoic acid methyl ester