1H-Imidazole, 4,5-dimethyl-1-(2-phenylethyl)-, 3-oxide

Base Information

Chemical Name:1H-Imidazole, 4,5-dimethyl-1-(2-phenylethyl)-, 3-oxide
CAS No.:65383-34-8
Molecular Formula:C13H16N2O
Molecular Weight:216.283
Hs Code.:
DSSTox Substance ID:DTXSID00456927
Wikidata:Q82279552

Synonyms:65383-34-8;1H-Imidazole, 4,5-dimethyl-1-(2-phenylethyl)-, 3-oxide;DTXSID00456927

Suppliers and Price of 1H-Imidazole, 4,5-dimethyl-1-(2-phenylethyl)-, 3-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1H-Imidazole, 4,5-dimethyl-1-(2-phenylethyl)-, 3-oxide

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:216.126263138
Heavy Atom Count:16
Complexity:216

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C([N+](=CN1CCC2=CC=CC=C2)[O-])C

Technology Process of 1H-Imidazole, 4,5-dimethyl-1-(2-phenylethyl)-, 3-oxide

There total 3 articles about 1H-Imidazole, 4,5-dimethyl-1-(2-phenylethyl)-, 3-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 149-73-5
trimethyl orthoformate

: 774222-86-5
3-[(2-phenylethyl)amino]butan-2-one oxime

: 65383-34-8
4,5-dimethyl-1-(2-phenylethyl)-1H-imidazole N³-oxide

Guidance literature:: With acetic acid; at 20 ℃; for 168h;
DOI:10.1055/s-2004-831212

Reference yield: 6.0%

: 774222-86-5
3-[(2-phenylethyl)amino]butan-2-one oxime

: 65383-34-8
4,5-dimethyl-1-(2-phenylethyl)-1H-imidazole N³-oxide

Guidance literature:: With toluene-4-sulfonic acid; Heating;
DOI:10.1002/ardp.200300840

Reference yield:

: 64-04-0
phenethylamine

: 65383-34-8
4,5-dimethyl-1-(2-phenylethyl)-1H-imidazole N³-oxide

Guidance literature:: Multi-step reaction with 2 steps

1.1: ZnCl₂ / methanol / 24 h / 20 °C

1.2: 48 percent / NaCN*BH₃ / methanol / 48 h / 20 °C

2.1: 6 percent / p-TsOH / Heating

With toluene-4-sulfonic acid; zinc(II) chloride; In methanol;
DOI:10.1002/ardp.200300840