Palmatine iodide

Base Information

• Chemical Name: Palmatine iodide
• CAS No.: 4880-79-9
• Molecular Formula: C21H22INO4
• Molecular Weight: 352.4031
• UNII: REY4ILD57Z
• DSSTox Substance ID: DTXSID30964121
• Wikidata: Q27288085
• ChEMBL ID: CHEMBL510114
• Mol file: 4880-79-9.mol

Synonyms:berbericinine;berbinium, 7,8,13,13a-tetradehydro-2,3,9,10-tetramethoxy-, chloride;berbinium, 7,8,13,13a-tetradehydro-2,3,9,10-tetramethoxy-, iodide;dibenzo(a,g)quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-, chloride (1:1);dibenzo(a,g)quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-, hydroxide (1:1);o,o-dimethyldemethyleneberberine;palmatine;palmatine cation;palmatine chloride;palmatine hydrochloride;palmatine hydroxide;palmatine iodide;palmatine ion;palmatine sulfate;palmatinium hydroxide;palmitine hydroxide

Chemical Property of Palmatine iodide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 40.80000
• Density: g/cm³
• LogP: 0.38880
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 479.05936
• Heavy Atom Count: 27
• Complexity: 475

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC.[I-]

Technology Process of Palmatine iodide

There total 14 articles about Palmatine iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(+/-)-tetrahydropalmatine (2934-97-6,84-38-8) → palmatine iodide (4880-79-9)

Guidance literature:

With iodine; potassium acetate; In methanol; Heating;

Reference yield: 78.0%

2,3-dihydroxy-9,10-dimethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium chloride + methyl iodide (74-88-4) → palmatine iodide (4880-79-9)

Guidance literature:

With sodium hydroxide; In methanol; at 20 ℃; Reflux;

DOI:10.1021/jm801157z

Reference yield:

(R)-(+)-tetrahydropalmatine (3520-14-7,84-38-8) → palmatine iodide (4880-79-9)

Guidance literature:

With iodine; In ethanol; Heating;

DOI:10.1016/S0040-4020(01)88546-X

upstream raw materials:

(R)-(+)-tetrahydropalmatine

(+/-)-tetrahydropalmatine

6,7-dimethoxyisoquinoline

6,7-dimethoxy-3,4-dihydro-isoquinoline

Downstream raw materials:

8-phenyldihydropalmatine