1,2-Bis(4-acetoxymethyl-3,5-dioxopiperazin-1-yl)ethane

Base Information

Chemical Name:1,2-Bis(4-acetoxymethyl-3,5-dioxopiperazin-1-yl)ethane
CAS No.:98631-87-9
Molecular Formula:C₁₆H₂₂N₄O₈
Molecular Weight:398.373
Hs Code.:
DSSTox Substance ID:DTXSID10243744
Nikkaji Number:J269.536G
Wikidata:Q83127899

Synonyms:ZSB 11;ZSB11;1,2-Bis(4-acetoxymethyl-3,5-dioxopiperazin-1-yl)ethane;2,6-Piperazinedione, 4,4'-(1,2-ethanediyl)bis(1-((acetyloxy)methyl)-;4,4'-(1,2-Ethanediyl)bis(1-((acetyloxy)methyl)-2,6-piperazinedione);98631-87-9;SCHEMBL10366813;DTXSID10243744;CFBQCRQDDJBRQF-UHFFFAOYSA-N;C16H22N4O8;C16-H22-N4-O8;LS-111886;4,4'-Ethylenebis(2,6-dioxopiperazine-1-methanol)bisacetate

Suppliers and Price of 1,2-Bis(4-acetoxymethyl-3,5-dioxopiperazin-1-yl)ethane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1,2-Bis(4-acetoxymethyl-3,5-dioxopiperazin-1-yl)ethane

Chemical Property:

Vapor Pressure:3.66E-15mmHg at 25°C
Boiling Point:617.2°Cat760mmHg
Flash Point:327.1°C
Density:1.364g/cm³
XLogP3:-1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:9
Exact Mass:398.14376367
Heavy Atom Count:28
Complexity:600

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OCN1C(=O)CN(CC1=O)CCN2CC(=O)N(C(=O)C2)COC(=O)C

Technology Process of 1,2-Bis(4-acetoxymethyl-3,5-dioxopiperazin-1-yl)ethane

There total 3 articles about 1,2-Bis(4-acetoxymethyl-3,5-dioxopiperazin-1-yl)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 108-24-7
acetic anhydride

: 98631-86-8
4,4'-(1,2-ethanediyl)bis(1-hydroxymethyl-2,6-piperazinedione)

: 98631-87-9
1,2-bis(4-acetoxymethyl-3,5-dioxopiperazin-1-yl)ethane

Guidance literature:: With pyridine; for 12h; Ambient temperature;
DOI:10.1248/cpb.37.2976

Reference yield: 70.5%

: 98631-86-8
4,4'-(1,2-ethanediyl)bis(1-hydroxymethyl-2,6-piperazinedione)

: 98631-87-9
1,2-bis(4-acetoxymethyl-3,5-dioxopiperazin-1-yl)ethane

Guidance literature:: With pyridine; acetic anhydride;

Reference yield:

: 1506-47-4
1,2-bis(3,5-dioxopiperazin-1-yl)-ethane

: 98631-87-9
1,2-bis(4-acetoxymethyl-3,5-dioxopiperazin-1-yl)ethane

Guidance literature:: Multi-step reaction with 2 steps

1: 64.7 percent / dimethylformamide; H₂O / 1.5 h / 130 °C

2: 71 percent / pyridine / 12 h / Ambient temperature

With pyridine; In water; N,N-dimethyl-formamide;
DOI:10.1248/cpb.37.2976