7-Chloroquinoline-2-carbonitrile

Base Information

Chemical Name:7-Chloroquinoline-2-carbonitrile
CAS No.:65482-29-3
Molecular Formula:C10H5ClN2
Molecular Weight:188.61300
Hs Code.:2933499090
European Community (EC) Number:890-313-6
Nikkaji Number:J1.420.261G

Synonyms:7-Chloroquinoline-2-carbonitrile;65482-29-3;SB68081;EN300-8105359;A867662

Suppliers and Price of 7-Chloroquinoline-2-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
7-Chloroquinoline-2-carbonitrile 95+%
1g
$ 614.00

Chemenu
7-Chloroquinoline-2-carbonitrile 95%
1g
$ 574.00

Alichem
7-Chloroquinoline-2-carbonitrile
1g
$ 529.65

Total 6 raw suppliers

Chemical Property of 7-Chloroquinoline-2-carbonitrile

Chemical Property:

PSA：36.68000
LogP:2.75988
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:188.0141259
Heavy Atom Count:13
Complexity:232

Purity/Quality:

97% ^*data from raw suppliers

7-Chloroquinoline-2-carbonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC2=C1C=CC(=N2)C#N)Cl

Technology Process of 7-Chloroquinoline-2-carbonitrile

There total 5 articles about 7-Chloroquinoline-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 7677-24-9
trimethylsilyl cyanide

: 7-chloroquinoline N-oxide

: 65482-29-3
7-chloroquinoline-2-carbonitrile

Guidance literature:: With [bis(acetoxy)iodo]benzene; In 1,2-dichloro-ethane; at 80 ℃; regioselective reaction;
DOI:10.1002/adsc.201801185

Reference yield: 60.0%

: 4965-33-7
2-methyl-7-chloroquinoline

: 65482-29-3
7-chloroquinoline-2-carbonitrile

Guidance literature:: With tert.-butylhydroperoxide; ammonium fluoride; oxygen; potassium iodide; In water; dimethyl sulfoxide; at 70 ℃; for 48h; Schlenk technique; Sealed tube;
DOI:10.1039/c5cc01024a

Reference yield:

: 612-61-3
7-chloroquinoline

: 65482-29-3
7-chloroquinoline-2-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; dihydrogen peroxide / 36 h / 70 °C

2: [bis(acetoxy)iodo]benzene / 1,2-dichloro-ethane / 80 °C

With [bis(acetoxy)iodo]benzene; dihydrogen peroxide; acetic acid; In 1,2-dichloro-ethane;
DOI:10.1002/adsc.201801185