3-BENZYLIDENE-2-OXO-CYCLOHEXANECARBALDEHYDE

Base Information

• Chemical Name: 3-BENZYLIDENE-2-OXO-CYCLOHEXANECARBALDEHYDE
• CAS No.: 69009-80-9
• Molecular Formula: C14H14O2
• Molecular Weight: 214.264
• Hs Code.: 2914400090
• Mol file: 69009-80-9.mol

Synonyms:3-BENZYLIDENE-2-OXO-CYCLOHEXANECARBALDEHYDE;

Chemical Property of 3-BENZYLIDENE-2-OXO-CYCLOHEXANECARBALDEHYDE

Chemical Property:

• Vapor Pressure: 4.43E-06mmHg at 25°C
• Boiling Point: 383.3°C at 760 mmHg
• Flash Point: 143.7°C
• PSA: 34.14000
• Density: 1.208g/cm³
• LogP: 2.63810

Purity/Quality:

99% ^*data from raw suppliers

3-BENZYLIDENE-2-OXO-CYCLOHEXANECARBALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-BENZYLIDENE-2-OXO-CYCLOHEXANECARBALDEHYDE

There total 5 articles about 3-BENZYLIDENE-2-OXO-CYCLOHEXANECARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-benzylidene-6-<(dimethylamino)methylidene>cyclohexanone (181428-60-4) → 3-benzylidene-2-oxocyclohexanecarboxaldehyde (69009-80-9)

Guidance literature:

With hydrogenchloride; In dichloromethane;

DOI:10.1021/ja00089a008

Reference yield:

(E)-2-benzylidenecyclohexanone (5682-83-7,31021-02-0,1467-15-8) → 3-benzylidene-2-oxocyclohexanecarboxaldehyde (69009-80-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / dimethylformamide / 3.5 h / Heating

2: 94 percent / 2 N HCl / CH₂Cl₂

With hydrogenchloride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja00089a008

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → 3-benzylidene-2-oxocyclohexanecarboxaldehyde (69009-80-9)

Guidance literature:

Multi-step reaction with 3 steps

1: KOH

2: 91 percent / dimethylformamide / 3.5 h / Heating

3: 94 percent / 2 N HCl / CH₂Cl₂

With hydrogenchloride; potassium hydroxide; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja00089a008

upstream raw materials:

(E)-2-benzylidenecyclohexanone

formic acid ethyl ester

2-benzylidene-6-<(dimethylamino)methylidene>cyclohexanone

cyclohexanone

Downstream raw materials:

2-<<(3,4-dimethoxyphenyl)methyl>amino>-8-oxo-5,6,7,8-tetrahydroquinoline-3-carboxylic acid ethyl ester

Refernces