p-(2,3-Dihydroxypropoxy)benzoic acid propyl ester

Base Information

• Chemical Name: p-(2,3-Dihydroxypropoxy)benzoic acid propyl ester
• CAS No.: 67032-34-2
• Molecular Formula: C13H18O5
• Molecular Weight: 254.279
• Mol file: 67032-34-2.mol

Synonyms:Propyl p-(2,3-dihydroxypropoxy)benzoate;BENZOIC ACID,p-(2,3-DIHYDROXYPROPOXY)-,PROPYL ESTER;

Chemical Property of p-(2,3-Dihydroxypropoxy)benzoic acid propyl ester

Chemical Property:

• Vapor Pressure: 3.78E-08mmHg at 25°C
• Boiling Point: 429.7°Cat760mmHg
• Flash Point: 161.4°C
• PSA: 75.99000
• Density: 1.195g/cm³
• LogP: 0.98540

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of p-(2,3-Dihydroxypropoxy)benzoic acid propyl ester

There total 1 articles about p-(2,3-Dihydroxypropoxy)benzoic acid propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

nipasol (94-13-3) + 3-monochloro-1,2-propanediol (96-24-2) → propyl 4-(2,3-dihydroxypropoxy)benzoate (67032-34-2)

Guidance literature:

With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 90 ℃; for 30h; Inert atmosphere;

DOI:10.1002/cjoc.201400121

Reference yield: 54.0%

propyl 4-(2,3-dihydroxypropoxy)benzoate (67032-34-2) → 4-(2,3-dihydroxypropoxy)benzohydrazide (103385-03-1)

Guidance literature:

With hydrazine hydrate; In ethanol; for 50h; Reflux;

DOI:10.1002/cjoc.201400121

Reference yield:

propyl 4-(2,3-dihydroxypropoxy)benzoate (67032-34-2) → C21H18AlN2O5(1+)*NO3(1-)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazine hydrate / ethanol / 50 h / Reflux

2: acetic acid / methanol / 8 h / Reflux; Inert atmosphere

3: aq. buffer

With hydrazine hydrate; acetic acid; In methanol; ethanol;

DOI:10.1002/cjoc.201400121

upstream raw materials:

nipasol

3-monochloro-1,2-propanediol

Downstream raw materials:

4-(2,3-dihydroxypropoxy)benzohydrazide