3-Methoxybenzidine

Base Information

• Chemical Name: 3-Methoxybenzidine
• CAS No.: 3365-87-5
• Molecular Formula: C₁₃H₁₄N₂O
• Molecular Weight: 214.267
• Hs Code.: 2922299090
• DSSTox Substance ID: DTXSID50187330
• Wikidata: Q83058994
• Mol file: 3365-87-5.mol

Synonyms:3-methoxybenzidine

Chemical Property of 3-Methoxybenzidine

Chemical Property:

• Boiling Point: 374.5oC at 760 mmHg
• Flash Point: 196.2oC
• PSA: 61.27000
• Density: 1.169g/cm3
• LogP: 3.68900
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 214.110613074
• Heavy Atom Count: 16
• Complexity: 214

Purity/Quality:

98%Min ^*data from raw suppliers

3-METHOXYBENZIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=CC(=C1)C2=CC=C(C=C2)N)N

Technology Process of 3-Methoxybenzidine

There total 4 articles about 3-Methoxybenzidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-phenyl-N'-2-methoxyphenyl hydrazine (952-35-2) → 3-Methoxy-benzidin (3365-87-5)

Guidance literature:

With hydrogenchloride;

Reference yield:

2-(hydroxymethyl)azobenzene (6319-21-7) → 3-Methoxy-benzidin (3365-87-5)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc; aq.-ethanolic NaOH

2: aq.-ethanolic HCl

With hydrogenchloride; sodium hydroxide; zinc;

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + N-phenyl-N'-2-methoxyphenyl hydrazine (952-35-2) → 3-Methoxy-benzidin (3365-87-5)

Guidance literature:

at -5 ℃; Rate constant; sowie bei 0grad und +9grad;

DOI:10.1021/ja01100a032

upstream raw materials:

N-phenyl-N'-2-methoxyphenyl hydrazine

hydrogenchloride

2-(hydroxymethyl)azobenzene

Downstream raw materials:

3-hydroxy-benzidine