(3-(3-Bromophenyl)propoxy)(tert-butyl)dimethylsilane

Base Information

Chemical Name:(3-(3-Bromophenyl)propoxy)(tert-butyl)dimethylsilane
CAS No.:65537-55-5
Molecular Formula:C15H25BrOSi
Molecular Weight:329.352
Hs Code.:
European Community (EC) Number:838-542-2
DSSTox Substance ID:DTXSID00605751
Wikidata:Q82504120

Synonyms:65537-55-5;(3-(3-bromophenyl)propoxy)(tert-butyl)dimethylsilane;3-(3-bromophenyl)propoxy-tert-butyl-dimethylsilane;Silane, [3-(3-bromophenyl)propoxy](1,1-dimethylethyl)dimethyl-;[3-(3-BROMOPHENYL)PROPOXY](TERT-BUTYL)DIMETHYLSILANE;SCHEMBL3643273;DTXSID00605751;IQOXMZHATWZPHQ-UHFFFAOYSA-N;EN300-7425032

Suppliers and Price of (3-(3-Bromophenyl)propoxy)(tert-butyl)dimethylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (3-(3-Bromophenyl)propoxy)(tert-butyl)dimethylsilane

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:6
Exact Mass:328.08580
Heavy Atom Count:18
Complexity:247

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)[Si](C)(C)OCCCC1=CC(=CC=C1)Br

Technology Process of (3-(3-Bromophenyl)propoxy)(tert-butyl)dimethylsilane

There total 4 articles about (3-(3-Bromophenyl)propoxy)(tert-butyl)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 65537-54-4
3-(3-bromophenyl)-propan-1-ol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 65537-55-5
1-bromo-3-[3-(tert-butyldimethylsilyloxy)-propyl]benzene

Guidance literature:: With triethylamine; dmap; In dichloromethane; at 20 ℃; for 18h;

Reference yield:

: 288-32-4
1H-imidazole

: 65537-54-4
3-(3-bromophenyl)-propan-1-ol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 65537-55-5
1-bromo-3-[3-(tert-butyldimethylsilyloxy)-propyl]benzene

Guidance literature:: In N-methyl-acetamide;

Reference yield:

: 42287-90-1
3-(3-bromophenyl)propanoic acid

: 65537-55-5
1-bromo-3-[3-(tert-butyldimethylsilyloxy)-propyl]benzene

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 20 °C

2: 1H-imidazole / N,N-dimethyl-formamide / 20 °C

With 1H-imidazole; lithium aluminium tetrahydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/anie.201712731