N-(4-CHLOROBENZYL)UREA

Base Information

• Chemical Name: N-(4-CHLOROBENZYL)UREA
• CAS No.: 65608-74-4
• Molecular Formula: C8H9ClN2O
• Molecular Weight: 184.625
• Hs Code.: 2924210090
• Mol file: 65608-74-4.mol

Synonyms:(4-Chlor-benzyl)-harnstoff;(4-chloro-benzyl)-urea;p-chlorobenzylurea;4-chlorobenzylurea;(4-chlorobenzylamine)monocarboxamide;

Chemical Property of N-(4-CHLOROBENZYL)UREA

Chemical Property:

• Melting Point: 198-200°
• PSA: 55.12000
• LogP: 2.59950

Purity/Quality:

97% ^*data from raw suppliers

N-(4-Chlorobenzyl)urea ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(4-CHLOROBENZYL)UREA

There total 11 articles about N-(4-CHLOROBENZYL)UREA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

potassium cyanate (590-28-3) + 4-chlorobenzylamine (104-86-9) → N-(4-chlorobenzyl)urea (65608-74-4)

Guidance literature:

With hydrogenchloride; In water; at 80 ℃; for 1h; Microwave irradiation;

DOI:10.1055/s-0030-1258553

Reference yield: 67.0%

nitrourea (556-89-8) + 4-chlorobenzylamine (104-86-9) → N-(4-chlorobenzyl)urea (65608-74-4)

Guidance literature:

In water; at 70 ℃;

DOI:10.1007/BF00772117

Reference yield: 60.0%

N-(4-chlorobenzyl)thiourea (24827-37-0) → N-(4-chlorobenzyl)urea (65608-74-4)

Guidance literature:

With hydrogenchloride; methanesulfonic acid; tetrabutylammomium bromide; In dimethyl sulfoxide; at 35 ℃; for 3h;

DOI:10.1002/jhet.5570370110

upstream raw materials:

potassium cyanate

4-chlorobenzylamine

(4-chlorophenyl)methanamine hydrochloride

nitrourea

Downstream raw materials:

N-nitroso-N-(p-chlorobenzyl)urea

(4-chloro-benzyl)-imidazolidinetrione

[3-(4-Chloro-benzyl)-2,4,5-trioxo-imidazolidin-1-yl]-acetic acid ethyl ester

1-(4-chlorobenzyl)-3-cyanoacetyl-urea