7-Oxooctanoic acid, 2-trimethylsilylethyl ester

Base Information

• Chemical Name: 7-Oxooctanoic acid, 2-trimethylsilylethyl ester
• CAS No.: 65690-30-4
• Molecular Formula: C₁₃H₂₆O₃Si
• Molecular Weight: 258.433
• Hs Code.: 2931900090
• Mol file: 65690-30-4.mol

Synonyms:7-OXOOCTANOIC ACID 2-TRIMETHYLSILYLETHYL ESTER;2-(Trimethylsilyl)ethyl 7-oxooctanoate;7-Oxo-octansaeure-(2-trimethylsilyl-ethylester);

Chemical Property of 7-Oxooctanoic acid, 2-trimethylsilylethyl ester

Chemical Property:

• PSA: 43.37000
• LogP: 3.40730

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-Oxooctanoic acid, 2-trimethylsilylethyl ester

There total 2 articles about 7-Oxooctanoic acid, 2-trimethylsilylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trimethylsilanyl-acetic acid ethyl ester (4071-88-9) → 7-Oxo-octansaeure-(2-trimethylsilyl-ethylester) (65690-30-4)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether / Heating

2: (i) (COCl)2, (ii) /BRN= 1732034/, Py

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1002/hlca.19770600856

Reference yield:

7-oxooctanoic acid (14112-98-2) + 2-(Trimethylsilyl)ethanol (2916-68-9) → 7-Oxo-octansaeure-(2-trimethylsilyl-ethylester) (65690-30-4)

Guidance literature:

Multistep reaction; (i) (COCl)2, (ii) /BRN= 1732034/, Py;

DOI:10.1002/hlca.19770600856

Reference yield:

7-Oxo-octansaeure-(2-trimethylsilyl-ethylester) (65690-30-4) → (+/-)-7-<(3,5-Bis-benzyloxy-phenyl)-acetoxy>-octansaeure-<2-trimethylsilyl-aethylester> (65690-34-8)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄ / propan-2-ol

2: (i) (COCl)2, (ii) /BRN= 3943961/, K₂CO₃, benzene

With sodium tetrahydroborate; In isopropyl alcohol;

DOI:10.1002/hlca.19770600856

upstream raw materials:

7-oxooctanoic acid

2-(Trimethylsilyl)ethanol

trimethylsilanyl-acetic acid ethyl ester

Downstream raw materials:

(+/-)-7-<(3,5-Bis-benzyloxy-phenyl)-acetoxy>-octansaeure-<2-trimethylsilyl-aethylester>