Aurodox

Base Information

Chemical Name:Aurodox
CAS No.:12704-90-4
Molecular Formula:C₄₄H₆₂N₂O₁₂
Molecular Weight:810.982
Hs Code.:
Mol file:12704-90-4.mol

Synonyms:2H-Pyran-2-acetamide,N-[(2E,4E,6S,7R)-7-[(2S,3S,4R,5R)-5-[(1E,3E,5E)-7-(1,2-dihydro-4-hydroxy-1-methyl-2-oxo-3-pyridinyl)-6-methyl-7-oxo-1,3,5-heptatrienyl]tetrahydro-3,4-dihydroxy-2-furanyl]-6-methoxy-5-methyl-2,4-octadienyl]-a-ethyltetrahydro-2,3,4-trihydroxy-5,5-dimethyl-6-(1E,3Z)-1,3-pentadienyl-,(aS,2R,3R,4R,6S)- (9CI); Mocimycin,1-methyl-; Antibiotic X 5108; Aurodox; Goldinodox; Goldinomycin; X 5108

Suppliers and Price of Aurodox

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Aurodox
1mg
$ 472.00

Usbiological
Aurodox
1mg
$ 456.00

TRC
Aurodox
0.5mg
$ 190.00

Cayman Chemical
Aurodox
1mg
$ 124.00

Cayman Chemical
Aurodox
500μg
$ 65.00

Cayman Chemical
Aurodox
5mg
$ 488.00

American Custom Chemicals Corporation
AURODOX 95.00%
5MG
$ 515.00

Adipogen Life Sciences
Aurodox ≥95%(HPLC)
2.5 mg
$ 490.00

Total 9 raw suppliers

Chemical Property of Aurodox

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:930.5°Cat760mmHg
PKA:pKa = 6.1(at 25℃)
Flash Point:516.5°C
PSA：217.24000
Density:1.271g/cm³
LogP:3.47610

Purity/Quality:

98%Min ^*data from raw suppliers

Aurodox ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Aurodox is a compound that inhibits bacterial protein biosynthesis.

Technology Process of Aurodox

There total 11 articles about Aurodox which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 94958-27-7
4-O-(p-methoxybenzyl)aurodox

: 12704-90-4
aurodox

Guidance literature:: With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In methanol; at 25 ℃; for 0.0833333h;
DOI:10.1021/ja00292a039

Reference yield:

: 94958-21-1
{(2E,4E)-(6S,7R)-7-[(3aR,4S,6R,6aS)-2,2-Dimethyl-6-((E)-3-oxo-propenyl)-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-6-methoxy-5-methyl-octa-2,4-dienyl}-carbamic acid 2,2,2-trichloro-ethyl ester

: 12704-90-4
aurodox

Guidance literature:: Multi-step reaction with 8 steps

1: NaN(SiMe₃)2 / toluene / 0.5 h / -78 - 0 °C

2: Me₃SiI / CH₂Cl₂ / 0.03 h / 0 °C

3: amberlyst-15 / dimethylformamide; H₂O / 25 °C

4: n-Bu₄NI / tetrahydrofuran / 25 °C

5: Zn / tetrahydrofuran / 25 °C / pH 7.2

6: CH₂Cl₂ / 25 °C

8: DDQ / methanol / 0.08 h / 25 °C

With amberlyst-15; trimethylsilyl iodide; sodium hexamethyldisilazane; tetra-(n-butyl)ammonium iodide; 2,3-dicyano-5,6-dichloro-p-benzoquinone; zinc; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ja00292a039

Reference yield:

: [(E)-4-(4-Benzyloxy-1-methyl-2-oxo-1,2-dihydro-pyridin-3-yl)-3-methyl-4-oxo-but-2-enyl]-triphenyl-phosphonium; bromide

: 12704-90-4
aurodox

Guidance literature:: Multi-step reaction with 8 steps

1: NaN(SiMe₃)2 / toluene / 0.5 h / -78 - 0 °C

2: Me₃SiI / CH₂Cl₂ / 0.03 h / 0 °C

3: amberlyst-15 / dimethylformamide; H₂O / 25 °C

4: n-Bu₄NI / tetrahydrofuran / 25 °C

5: Zn / tetrahydrofuran / 25 °C / pH 7.2

6: CH₂Cl₂ / 25 °C

8: DDQ / methanol / 0.08 h / 25 °C

With amberlyst-15; trimethylsilyl iodide; sodium hexamethyldisilazane; tetra-(n-butyl)ammonium iodide; 2,3-dicyano-5,6-dichloro-p-benzoquinone; zinc; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ja00292a039