Diethyl (2,3,5,6-tetrafluoropyridin-4-yl)phosphonate

Base Information

Chemical Name:Diethyl (2,3,5,6-tetrafluoropyridin-4-yl)phosphonate
CAS No.:65748-23-4
Molecular Formula:C₉H₁₀F₄NO₃P
Molecular Weight:287.151
Hs Code.:
DSSTox Substance ID:DTXSID90500246
Wikidata:Q82351695

Synonyms:65748-23-4;Diethyl (2,3,5,6-tetrafluoropyridin-4-yl)phosphonate;DTXSID90500246

Suppliers and Price of Diethyl (2,3,5,6-tetrafluoropyridin-4-yl)phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Diethyl (2,3,5,6-tetrafluoropyridin-4-yl)phosphonate

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:287.03344283
Heavy Atom Count:18
Complexity:298

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOP(=O)(C1=C(C(=NC(=C1F)F)F)F)OCC

Technology Process of Diethyl (2,3,5,6-tetrafluoropyridin-4-yl)phosphonate

There total 2 articles about Diethyl (2,3,5,6-tetrafluoropyridin-4-yl)phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1603-79-8
phenylglyoxylic acid ethyl ester

: 700-16-3
Pentafluoropyridine

: 120341-31-3
tert-butyldimethylsilyloxydiethyl phosphonic ester

: ethyl 2-(diethoxyphosphoryloxy)-2-(2,3,5,6-tetrafluoropyridin-4-yl)-2-phenylacetate

: 65748-23-4
2,3,5,6-Tetrafluor-4-pyridylphosphonsaeure-diethylester

Guidance literature:: With 1-tert-butyl-2,2,4,4,4-pentakis(dimethylamino)-2Λ⁵,4Λ⁵-catenadi(phosphazene); In tetrahydrofuran; at 20 ℃; for 4h; Reagent/catalyst; Inert atmosphere;
DOI:10.1002/chem.201803218

Reference yield:

: 1603-79-8
phenylglyoxylic acid ethyl ester

: 700-16-3
Pentafluoropyridine

: 120341-31-3
tert-butyldimethylsilyloxydiethyl phosphonic ester

: 21960-10-1
ethyl 2-((diethoxyphosphoryl)oxy)-2-phenylacetate

: ethyl 2-(diethoxyphosphoryloxy)-2-(2,3,5,6-tetrafluoropyridin-4-yl)-2-phenylacetate

: 65748-23-4
2,3,5,6-Tetrafluor-4-pyridylphosphonsaeure-diethylester

Guidance literature:: With 1-tert-butyl-2,2,4,4,4-pentakis(dimethylamino)-2Λ⁵,4Λ⁵-catenadi(phosphazene); In tetrahydrofuran; ethyl acetate; at 20 ℃; for 4h; Reagent/catalyst; Solvent; chemoselective reaction; Inert atmosphere;
DOI:10.1002/chem.201803218