Technology Process of Acridine, 9-(4-butylphenyl)-
There total 5 articles about Acridine, 9-(4-butylphenyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); potassium carbonate;
In
1,4-dioxane; water;
at 100 ℃;
for 8h;
Inert atmosphere;
DOI:10.1016/j.ejmech.2021.113480
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sulfuric acid / 6 h / 100 °C / Inert atmosphere
2: phosphorus tribromide / 24 h / 0 - 100 °C / Inert atmosphere
3: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 8 h / 100 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); sulfuric acid; phosphorus tribromide; potassium carbonate;
In
1,4-dioxane; water;
3: |Suzuki Coupling;
DOI:10.1016/j.ejmech.2021.113480
- Guidance literature:
-
Multi-step reaction with 4 steps
1: copper; potassium carbonate / ethanol / 12 h / Reflux
2: sulfuric acid / 6 h / 100 °C / Inert atmosphere
3: phosphorus tribromide / 24 h / 0 - 100 °C / Inert atmosphere
4: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 8 h / 100 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); sulfuric acid; phosphorus tribromide; copper; potassium carbonate;
In
1,4-dioxane; ethanol; water;
1: |Ullmann Condensation / 4: |Suzuki Coupling;
DOI:10.1016/j.ejmech.2021.113480
