p-Iodoclonidine

Base Information

Chemical Name:p-Iodoclonidine
CAS No.:108294-53-7
Molecular Formula:C₉H₈Cl₂IN₃
Molecular Weight:355.993
Hs Code.:2933290090
UNII:JJ25E6L8H3
Nikkaji Number:J448.134H
Wikidata:Q82880618
Pharos Ligand ID:1CAW3JLD9NRA
ChEMBL ID:CHEMBL360803
Mol file:108294-53-7.mol

Synonyms:4-iodoclonidine;p-iodoclonidine

Suppliers and Price of p-Iodoclonidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
p-Iodoclonidine Hydrochloride
10mg
$ 319.00

Sigma-Aldrich
p-Iodoclonidine hydrochloride analytical standard, for drug analysis
25 mg
$ 56.80

Sigma-Aldrich
p-Iodoclonidine hydrochloride analytical standard, for drug analysis
25mg-i
$ 55.00

American Custom Chemicals Corporation
P-IODOCLONIDINE HYDROCHLORIDE 95.00%
25MG
$ 596.06

Total 4 raw suppliers

Chemical Property of p-Iodoclonidine

Chemical Property:

Vapor Pressure:7.59E-06mmHg at 25°C
Boiling Point:375.8°Cat760mmHg
Flash Point:181.1°C
PSA：36.42000
Density:2.08g/cm³
LogP:4.23790
Solubility.:H2O: soluble
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:354.91400
Heavy Atom Count:15
Complexity:250

Purity/Quality:

95% ^*data from raw suppliers

p-Iodoclonidine Hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 20/21/22
Safety Statements: 36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1CN=C(N1)NC2=C(C=C(C=C2Cl)I)Cl
Uses p-Iodoclonidine Hydrochloride is a α2-Adrenergic agonist; and displays a high affinity for the α2-adrenergic receptor.

Technology Process of p-Iodoclonidine

There total 3 articles about p-Iodoclonidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108294-54-8
1-benzoyl-3-(2,6-dichloro-4-iodophenyl)thiourea

: 108294-53-7
p-[¹²⁵I]iodoclonidine

Guidance literature:: Multi-step reaction with 3 steps

1: 10percent aq. NaOH / 0.17 h / Heating

2: 98 percent / methanol / 2 h / Heating

3: ethanol / 18 h / 145 °C

With sodium hydroxide; In methanol; ethanol;
DOI:10.1021/jm00390a021

Reference yield:

: 68569-85-7
N-(2,6-dichloro-4-iodophenyl)-S-methylisothiourea hydroiodide

: 107-15-3,85404-18-8
ethylenediamine

: 108294-53-7
p-[¹²⁵I]iodoclonidine

Guidance literature:: In ethanol; at 145 ℃; for 18h;
DOI:10.1021/jm00390a021

Reference yield:

: 108294-55-9
(2,6-dichloro-4-iodophenyl)thiourea

: 108294-53-7
p-[¹²⁵I]iodoclonidine

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / methanol / 2 h / Heating

2: ethanol / 18 h / 145 °C

In methanol; ethanol;
DOI:10.1021/jm00390a021