1H-Pyridazino(4,5-b)indole-1,4(5H)-dione, 2,3-dihydro-

Base Information

Chemical Name:1H-Pyridazino(4,5-b)indole-1,4(5H)-dione, 2,3-dihydro-
CAS No.:80985-55-3
Molecular Formula:C₁₀H₇N₃O₂
Molecular Weight:201.184
Hs Code.:
DSSTox Substance ID:DTXSID60230826
Wikidata:Q83111560
Mol file:80985-55-3.mol

Synonyms:80985-55-3;BRN 0017487;1H-Pyridazino(4,5-b)indole-1,4(5H)-dione, 2,3-dihydro-;2,3-Dihydro-1H-pyridazino(4,5-b)indole-1,4(5H)-dione;4-26-00-00601 (Beilstein Handbook Reference);C10H7N3O2;3,5-dihydro-2H-pyridazino[4,5-b]indole-1,4-dione;Oprea1_001565;SCHEMBL19198253;DTXSID60230826;C10-H7-N3-O2;LS-129700

Suppliers and Price of 1H-Pyridazino(4,5-b)indole-1,4(5H)-dione, 2,3-dihydro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1H-PYRIDAZINO(4,5-B)INDOLE-1,4(5H)-DIONE, 2,3-DIHYDRO- 95.00%
5MG
$ 495.59

AccelPharmtech
2,3-dihydro-1H-Pyridazino[4,5-b]indole-1,4(5H)-dione 97.00%
25G
$ 5120.00

AccelPharmtech
2,3-dihydro-1H-Pyridazino[4,5-b]indole-1,4(5H)-dione 97.00%
5G
$ 2750.00

AccelPharmtech
2,3-dihydro-1H-Pyridazino[4,5-b]indole-1,4(5H)-dione 97.00%
1G
$ 2370.00

Total 4 raw suppliers

Chemical Property of 1H-Pyridazino(4,5-b)indole-1,4(5H)-dione, 2,3-dihydro-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：82.03000
Density:1.504g/cm³
LogP:1.52230
XLogP3:0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:201.053826475
Heavy Atom Count:15
Complexity:318

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

1H-PYRIDAZINO(4,5-B)INDOLE-1,4(5H)-DIONE, 2,3-DIHYDRO- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C3=C(N2)C(=O)NNC3=O

Technology Process of 1H-Pyridazino(4,5-b)indole-1,4(5H)-dione, 2,3-dihydro-

There total 5 articles about 1H-Pyridazino(4,5-b)indole-1,4(5H)-dione, 2,3-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 54781-93-0
1H-indole-2,3-dicarboxylic acid dimethyl ester

: 80985-55-3
1,4-dioxo-1,2,3,4-tetrahydro-5H-pyridazino<4,5-b>indole

Guidance literature:: With hydrazine hydrate monohydrate; In ethanol; for 5h; Heating;
DOI:10.3987/com-00-9049

Reference yield:

: 75400-67-8
indole-1-carboxylic acid tert-butyl ester

: 80985-55-3
1,4-dioxo-1,2,3,4-tetrahydro-5H-pyridazino<4,5-b>indole

Guidance literature:: Multi-step reaction with 5 steps

1: tetra-n-butylammonium perchlorate / acetonitrile / 0 °C / Electrolysis

2: diethyl ether / 0.17 h

3: trifluoroacetic acid / dichloromethane / 1 h / 0 - 20 °C

4: 2,3-dicyano-5,6-dichloro-p-benzoquinone / 1,4-dioxane / 1 h / 20 °C

5: hydrazine hydrate monohydrate / ethanol / 10 h / 100 °C

With tetra-n-butylammonium perchlorate; hydrazine hydrate monohydrate; trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; diethyl ether; ethanol; dichloromethane; acetonitrile;
DOI:10.1021/jacs.1c13032

Reference yield:

: C₁₅H₁₇NO₆

: 80985-55-3
1,4-dioxo-1,2,3,4-tetrahydro-5H-pyridazino<4,5-b>indole

Guidance literature:: Multi-step reaction with 4 steps

1: diethyl ether / 0.17 h

2: trifluoroacetic acid / dichloromethane / 1 h / 0 - 20 °C

3: 2,3-dicyano-5,6-dichloro-p-benzoquinone / 1,4-dioxane / 1 h / 20 °C

4: hydrazine hydrate monohydrate / ethanol / 10 h / 100 °C

With hydrazine hydrate monohydrate; trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; diethyl ether; ethanol; dichloromethane;
DOI:10.1021/jacs.1c13032