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DIMETHYL INDOLE-2,3-DICARBOXYLATE is an organic compound that serves as a versatile reactant in the synthesis of various pharmaceutical and chemical agents. It is characterized by its indole core and two carboxylate groups, which contribute to its reactivity and potential applications in different industries.

54781-93-0

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54781-93-0 Usage

Uses

Used in Pharmaceutical Industry:
DIMETHYL INDOLE-2,3-DICARBOXYLATE is used as a reactant for the preparation of indole-indolone scaffolds, which are important structural motifs in the development of novel drugs with diverse therapeutic properties.
Used in Analytical Chemistry:
DIMETHYL INDOLE-2,3-DICARBOXYLATE is used as a chemiluminescent agent, which is valuable for the detection and analysis of various chemical and biological substances due to its ability to emit light upon reaction.
Used in Cardiovascular Therapy:
DIMETHYL INDOLE-2,3-DICARBOXYLATE is used as an antihypertensive agent, helping to regulate blood pressure and maintain cardiovascular health by modulating the activity of certain enzymes or receptors involved in blood pressure regulation.
Used in Hemostasis Management:
DIMETHYL INDOLE-2,3-DICARBOXYLATE is used as an inhibitor of blood platelet aggregation, playing a crucial role in preventing blood clot formation and promoting proper blood flow, which is essential in the management of various cardiovascular conditions.
Used in Cardiac Function Regulation:
DIMETHYL INDOLE-2,3-DICARBOXYLATE is used as an inotropic agent, which helps to modulate the contractile force of the heart, thereby improving cardiac function and overall cardiovascular health.

Check Digit Verification of cas no

The CAS Registry Mumber 54781-93-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,7,8 and 1 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 54781-93:
(7*5)+(6*4)+(5*7)+(4*8)+(3*1)+(2*9)+(1*3)=150
150 % 10 = 0
So 54781-93-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO4/c1-16-11(14)9-7-5-3-4-6-8(7)13-10(9)12(15)17-2/h3-6,13H,1-2H3

54781-93-0 Well-known Company Product Price

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  • Aldrich

  • (370444)  Dimethyl2,3-indoledicarboxylate  98%

  • 54781-93-0

  • 370444-500MG

  • 1,350.18CNY

  • Detail

54781-93-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Dimethyl 1H-indole-2,3-dicarboxylate

1.2 Other means of identification

Product number -
Other names dimethyl 1H-indole-2,3-dicarboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:54781-93-0 SDS

54781-93-0Relevant academic research and scientific papers

Construction of spiro[indoline]oxindoles through one-pot thermal-induced [3+2] cycloaddition/silica gel-promoted fragmentation sequence between isatin ketonitrones and electron-deficient alkynes

Yang, Hai-Bin,Wei, Yin,Shi, Min

, p. 4088 - 4097 (2013/06/27)

One-pot thermal-induced [3+2] cycloaddition/silica gel-promoted fragmentation sequence between isatin ketonitrones and electron-deficient alkynes affords spiro[indoline]oxindoles in moderate to excellent yields along with good diastereoselectivities. The

Synthesis and reaction of dimethyl 7-bromoindole-2,3-dicarboxylates

Miki, Yasuyoshi,Matsushita, Ko-Ichi,Hibino, Hajime,Shirokoshi, Hideaki

, p. 1585 - 1596 (2007/10/03)

Reaction of 1-(4-benzyloxyphenyl)-2-phenylhydrazine with dimethyl acetylenedicarboxylate (DMAD) gave dimethyl 5-benzyloxyindole-2,3- dicarboxylate and dimethyl indole-2,3-dicarboxylate. However, treatment of 1- (2-bromophenyl)-2-phenylhydrazine with DMAD

Photochemistry of Dimethyl Quinoline-3,4-dicarboxylate N-Oxides

Irvine, Robert W.,Summers, John C.,Taylor, Walter C.

, p. 1419 - 1430 (2007/10/02)

The photochemical rearrangement of 2-methyl and 2-aryl substituted dimethyl quinoline-3,4-dicarboxylate N-oxides has been studied.In methanol or methanol/chloroform solutions the major product was the 1-methyl- or 1-aryl-quinolin-2-(1H)-one in which the substituent at C2 has migrated to nitrogen.The yield of these products was increased in a dark reaction subsequent to the irradiation.In acetonitrile solutions the initial major product was the corresponding 3,1-benzoxazepine; subsequent reactions yielded inter alia indole derivatives.

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