4-Methyl-1-piperazineacetic acid 2-(hydroxydiphenylacetyl)hydrazide

Base Information

Chemical Name:4-Methyl-1-piperazineacetic acid 2-(hydroxydiphenylacetyl)hydrazide
CAS No.:128156-85-4
Molecular Formula:C₂₁H₂₆N₄O₃
Molecular Weight:382.462
Hs Code.:
DSSTox Substance ID:DTXSID30155830
Wikidata:Q83023813
Mol file:128156-85-4.mol

Synonyms:BRN 4334543;4-Methyl-1-piperazineacetic acid 2-(hydroxydiphenylacetyl)hydrazide;128156-85-4;1-Piperazineacetic acid, 4-methyl-, 2-(hydroxydiphenylacetyl)hydrazide;DTXSID30155830;STL325679;AKOS022111439;LS-110076;2-hydroxy-N'-[(4-methylpiperazin-1-yl)acetyl]-2,2-diphenylacetohydrazide

Suppliers and Price of 4-Methyl-1-piperazineacetic acid 2-(hydroxydiphenylacetyl)hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Methyl-1-piperazineacetic acid 2-(hydroxydiphenylacetyl)hydrazide

Chemical Property:

Boiling Point:649.3°Cat760mmHg
Flash Point:346.5°C
Density:1.221g/cm³
XLogP3:1.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:382.20049070
Heavy Atom Count:28
Complexity:504

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)CC(=O)NNC(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O

Technology Process of 4-Methyl-1-piperazineacetic acid 2-(hydroxydiphenylacetyl)hydrazide

There total 3 articles about 4-Methyl-1-piperazineacetic acid 2-(hydroxydiphenylacetyl)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 109-01-3
1-methyl-piperazine

: 128156-76-3
OTUB₂-COV-10

: 128156-85-4
(4-Methyl-piperazin-1-yl)-acetic acid N'-(2-hydroxy-2,2-diphenyl-acetyl)-hydrazide

Guidance literature:: In 1,4-dioxane; for 2h; Heating;
DOI:10.1007/BF00764409

Reference yield:

: 96973-02-3
diphenylglycolic acid cyclohexylidene hydrazide

: 128156-85-4
(4-Methyl-piperazin-1-yl)-acetic acid N'-(2-hydroxy-2,2-diphenyl-acetyl)-hydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / hydrazine hydrate / ethanol / 0.25 h / Heating

2: 82 percent / dioxane / 2 h / Heating

3: 60 percent / dioxane / 2 h / Heating

With hydrazine hydrate; In 1,4-dioxane; ethanol;
DOI:10.1007/BF00764409

Reference yield:

: 13050-38-9
benzilic hydrazide

: 128156-85-4
(4-Methyl-piperazin-1-yl)-acetic acid N'-(2-hydroxy-2,2-diphenyl-acetyl)-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / dioxane / 2 h / Heating

2: 60 percent / dioxane / 2 h / Heating

In 1,4-dioxane;
DOI:10.1007/BF00764409