Piperidine, 1-trichloroacetyl-

Base Information

• Chemical Name: Piperidine, 1-trichloroacetyl-
• CAS No.: 2296-53-9
• Molecular Formula: C₇H₁₀Cl₃NO
• Molecular Weight: 230.522
• European Community (EC) Number: 666-226-2
• NSC Number: 203251
• DSSTox Substance ID: DTXSID80177507
• Wikidata: Q83047839
• Mol file: 2296-53-9.mol

Synonyms:Piperidine, 1-trichloroacetyl-;2296-53-9;2,2,2-trichloro-1-piperidin-1-ylethanone;Piperidine, 1-trichloroacetyl-,;2,2,2-trichloro-1-piperidinoethan-1-one;NSC203251;1-(Trichloroacetyl)piperidine;SCHEMBL14008175;1-(Trichloroacetyl)piperidine #;DTXSID80177507;COHUYGSEUCDFQT-UHFFFAOYSA-N;CCG-55982;AKOS003863995;NSC 203251;NSC-203251;1-(2,2,2-TRICHLOROACETYL)PIPERIDINE;SR-01000644977-1

Chemical Property of Piperidine, 1-trichloroacetyl-

Chemical Property:

• Vapor Pressure: 0.00715mmHg at 25°C
• Boiling Point: 269.7°Cat760mmHg
• Flash Point: 116.9°C
• Density: 1.414g/cm³
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 228.982797
• Heavy Atom Count: 12
• Complexity: 172

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)C(=O)C(Cl)(Cl)Cl

Technology Process of Piperidine, 1-trichloroacetyl-

There total 3 articles about Piperidine, 1-trichloroacetyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

piperidine (110-89-4) + 1,1,1,3,3,3-hexachloro-propan-2-one (116-16-5) → N-Trichloracetyl-piperidin (2296-53-9)

Guidance literature:

In tetrachloromethane; 1.) 20 min, -10 deg C, 2.) 2d, 20 deg C;

Reference yield:

piperidine (110-89-4) + trifluoroacetyl chloride (76-02-8) → N-Trichloracetyl-piperidin (2296-53-9)

Guidance literature:

With diethyl ether;

Reference yield:

→ N-Trichloracetyl-piperidin (2296-53-9)

Guidance literature:

Piperidin, Trichloracetylchlorid;

upstream raw materials:

piperidine

trifluoroacetyl chloride

1,1,1,3,3,3-hexachloro-propan-2-one