Isoalantolactone

Base Information

Chemical Name:Isoalantolactone
CAS No.:470-17-7
Molecular Formula:C15H20O2
Molecular Weight:232.323
Hs Code.:29322090
European Community (EC) Number:683-108-6
NSC Number:241036
UNII:BYH07P620U,QTF89ZHT7V
Nikkaji Number:J12.027H
Wikidata:Q27089356
Metabolomics Workbench ID:50008
ChEMBL ID:CHEMBL137803
Mol file:470-17-7.mol

Synonyms:isoalantolactone

Suppliers and Price of Isoalantolactone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Isoalantolactone
50mg
$ 333.00

Usbiological
Isoalantolactone
20mg
$ 320.00

Medical Isotopes, Inc.
Isoalantolactone
100 mg
$ 595.00

Labseeker
ISOALANTOACTONE 95
1g
$ 600.00

JR MediChem
isoalantolactone 98%
20mg
$ 300.00

DC Chemicals
Isoalantolactone >98%,StandardReferencesGrade
20 mg
$ 280.00

CSNpharm
Isoalantolactone
5mg
$ 43.00

CSNpharm
Isoalantolactone
10mg
$ 70.00

CSNpharm
Isoalantolactone
50mg
$ 163.00

Crysdot
Isoalantolactone 98+%
50mg
$ 170.00

Total 72 raw suppliers

Chemical Property of Isoalantolactone

Chemical Property:

Vapor Pressure:1.63E-05mmHg at 25°C
Melting Point:115℃
Refractive Index:1.527
Boiling Point:364.9 °C at 760 mmHg
Flash Point:152.7 °C
PSA：26.30000
Density:1.07 g/cm³
LogP:3.24060
Storage Temp.:2-8°C
Solubility.:Soluble in DMSO (up to 50 mg/ml) or ethanol (30 mg/ml)
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:232.146329876
Heavy Atom Count:17
Complexity:409

Purity/Quality:

HPLC>98.0% ^*data from raw suppliers

Isoalantolactone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 40
Safety Statements: 22-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCCC(=C)C1CC3C(C2)OC(=O)C3=C
Isomeric SMILES:C[C@]12CCCC(=C)[C@@H]1C[C@H]3[C@@H](C2)OC(=O)C3=C
Description Isohelenin (470-17-7) is a sesquiterpene lactone isolated from Mexican Indian medicinal plants known to have anti-inflammatory properties. A potent inhibitor of NFkB (complete inhibition at 5 μM)1 acting via inhibition of IKK?6. Isohelenin-mediated NFkB inhibition suppresses IL-8 expression2, iNOS expression3 and RANTES biosynthesis4. Displays protective effects in endotoxic shock in rodent models.5 Induces apoptosis in glioma cells.6
Uses Isoalantolactone is a sesquiterpene lactone used in the treatment of cancer. It can inhibit tumor cell growth and induce apoptosis.

Technology Process of Isoalantolactone

There total 32 articles about Isoalantolactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%