cis-1,2-dibromo-Cyclohexane

Base Information

• Chemical Name: cis-1,2-dibromo-Cyclohexane
• CAS No.: 19246-38-9
• Molecular Formula: C6H10Br2
• Molecular Weight: 241.953
• Hs Code.: 2903890090
• Nikkaji Number: J82.848C
• Mol file: 19246-38-9.mol

Synonyms:cis-1,2-dibromo-Cyclohexane;19246-38-9;1alpha,2alpha-Dibromocyclohexane;(1S,2R)-1,2-dibromocyclohexane;Cyclohexane, 1,2-dibromo-, cis-;(1R,2S)-1,2-dibromocyclohexane;cis-1,2-Dibromcyclohexan;SCHEMBL7052054;Cyclohexane,1,2-dibromo-,cis-

Chemical Property of cis-1,2-dibromo-Cyclohexane

Chemical Property:

• Melting Point: 9.7°C
• Refractive Index: 1.5514 (estimate)
• Boiling Point: 220.5°Cat760mmHg
• Flash Point: 91.5°C
• PSA: 0.00000
• Density: 1.789g/cm³
• LogP: 3.08740
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 241.91288
• Heavy Atom Count: 8
• Complexity: 62.9

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(C(C1)Br)Br
• Isomeric SMILES: C1CC[C@@H]([C@@H](C1)Br)Br

Technology Process of cis-1,2-dibromo-Cyclohexane

There total 12 articles about cis-1,2-dibromo-Cyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

cyclohexene (110-83-8) → cis-1,2-dibromocyclohexane (19246-38-9) + cis-2-bromocyclohexanol (2425-33-4,16536-57-5,24796-87-0,53023-24-8,53023-25-9,60933-67-7,5537-67-7)

Guidance literature:

With potassium bromate; sulfuric acid; water; potassium bromide; In dimethyl sulfoxide; at 70 - 80 ℃; for 0.5h;

DOI:10.1016/j.tet.2009.01.095

Reference yield: 80.0%

cyclohexene (110-83-8) → cis-1,2-dibromocyclohexane (19246-38-9)

Guidance literature:

With bromine; iodobis(N,N-diisopropyldithiocarbamato)iron(III); In dichloromethane; at 20 ℃;

DOI:10.1039/c39850001404

Reference yield: 72.0%

cyclohexene (110-83-8) → cis-1,2-dibromocyclohexane (19246-38-9) + trans-1,2-dibromocyclohexane (7429-37-0)

Guidance literature:

With pyrrolidine; Succinimide; N-Bromosuccinimide; In chloroform; at 60 ℃; for 6h; optical yield given as %de; diastereoselective reaction;

DOI:10.1016/j.tetlet.2010.03.043

upstream raw materials:

1-bromocyclohex-1-ene

1-bromocyclohexane

cyclohexene

hydrogen bromide

Downstream raw materials:

cyclohexene

bromine

1-bromocyclohex-1-ene

cis-cyclohexane-1,2-dicarbonitrile

Refernces

• 1、 Agrawal, Manoj K.,Adimurthy, Subbarayappa,Ganguly, Bishwajit,Ghosh, Pushpito K.. "Comparative study of the vicinal functionalization of olefins with 2:1 bromide/bromate and iodide/iodate reagents". experimental part. p. 2791 - 2797. Retrieved 2009/08/08.
• 2、 Tsipis, Constantinos A.,Katsoulos, George A.,Vakoulis, Fotios D.. "Halogenobis(N,N-dialkyldithiocarbamato)iron(III) Complexes as Potential Catalysts for Halogen Addition Reactions to Alkenes". . p. 1404 - 1405. Retrieved 2007/10/02.