Technology Process of 2,2-Pyrrolidinedicarboxylic acid, 3,5-diphenyl-, diethyl ester
There total 7 articles about 2,2-Pyrrolidinedicarboxylic acid, 3,5-diphenyl-, diethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; sodium cyanoborohydride;
In
methanol; water;
DOI:10.1039/c2ob26423d
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / dichloromethane / 15 h / Reflux
2.1: hydroxylamine hydrochloride; triethylamine / ethanol / 7 h / Reflux
3.1: sodium / ethanol / 0.5 h / 20 °C
3.2: 0 °C
4.1: sodium hydride / tetrahydrofuran / 0.5 h / Reflux
5.1: sodium cyanoborohydride; hydrogenchloride / methanol; water
With
hydrogenchloride; hydroxylamine hydrochloride; sodium; sodium hydride; sodium cyanoborohydride; potassium carbonate; triethylamine;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water;
1.1: |Michael Addition;
DOI:10.1039/c2ob26423d
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / dichloromethane / 15 h / Reflux
2.1: hydroxylamine hydrochloride; triethylamine / ethanol / 7 h / Reflux
3.1: sodium / ethanol / 0.5 h / 20 °C
3.2: 0 °C
4.1: sodium hydride / tetrahydrofuran / 0.5 h / Reflux
5.1: sodium cyanoborohydride; hydrogenchloride / methanol; water
With
hydrogenchloride; hydroxylamine hydrochloride; sodium; sodium hydride; sodium cyanoborohydride; potassium carbonate; triethylamine;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water;
1.1: |Michael Addition;
DOI:10.1039/c2ob26423d
