Methionine

Base Information

• Chemical Name: Methionine
• CAS No.: 3654-96-4
• Deprecated CAS: 24425-78-3,7005-18-7,1437749-32-0,1437749-60-4,1437749-65-9,1437749-75-1,1437749-80-8,1437769-00-0,1437870-94-4,1437870-95-5,1437870-97-7,1437870-98-8,1437871-20-9,1463481-01-7,1463481-06-2,1463481-15-3,1463481-19-7,1463481-23-3,1463481-27-7,1463481-31-3,1463481-37-9,1463481-41-5,1463481-46-0,1463481-51-7,1463481-58-4,1463481-73-3,1463481-80-2,1463481-89-1,1463610-75-4,1463610-76-5,1466415-57-5,1437749-32-0,1437749-60-4,1437749-65-9,1437749-75-1,1437749-80-8,1437769-00-0,1437870-94-4,1437870-95-5,1437870-97-7,1437870-98-8,1437871-20-9,1463481-06-2,1463481-15-3,1463481-19-7,1463481-23-3,1463481-27-7,1463481-31-3,1463481-37-9,1463481-41-5,1463481-46-0,1463481-51-7,1463481-58-4,1463481-73-3,1463481-80-2,1463481-89-1,1463610-75-4,1463610-76-5,1466415-57-5,7005-18-7
• Molecular Formula: C₅H₁₁NO₂S
• Molecular Weight: 152.148
• European Community (EC) Number: 200-562-9
• NSC Number: 760117
• UNII: AE28F7PNPL
• DSSTox Substance ID: DTXSID5040548
• Nikkaji Number: J9.174J
• Wikipedia: Methionine
• Wikidata: Q22124685
• NCI Thesaurus Code: C29600
• RXCUI: 6837
• Metabolomics Workbench ID: 37371
• ChEMBL ID: CHEMBL42336
• Mol file: 3654-96-4.mol

Synonyms:L-Isomer Methionine;L-Methionine;Liquimeth;Methionine;Methionine, L Isomer;Methionine, L-Isomer;Pedameth

Chemical Property of Methionine

Chemical Property:

• Melting Point: 280-282oC
• Boiling Point: 306.9 °C at 760 mmHg
• Flash Point: 139.4 °C
• PSA: 88.62000
• Density: 1.206 g/cm³
• LogP: 0.85170
• XLogP3: -1.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 149.05104977
• Heavy Atom Count: 9
• Complexity: 97

Purity/Quality:

99%, ^*data from raw suppliers

L-35S-METHIONINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Biological Agents -> Amino Acids and Derivatives
• Canonical SMILES: CSCCC(C(=O)O)N
• Isomeric SMILES: CSCC[C@@H](C(=O)O)N
• Recent ClinicalTrials: GnRHa + Letrozole in Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients
• Recent EU Clinical Trials: NA
• Recent NIPH Clinical Trials: Molecular Imaging using amino-acid PET tracer: Clinical research for diagnostic and therapeutic evaluation with amino acid PET tracer for multiple myeloma

Technology Process of Methionine

There total 1 articles about Methionine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 7.0%

D-Glucose (2280-44-6) → (35)S-methionine (3654-96-4) + [35S]-L-cysteine (24321-12-8)

Guidance literature:

With diammonium phosphate; dipotassium hydrogenphosphate; potassium dihydrogenphosphate; 5-hydroxy-6-methyl-3,4-pyridinedimethanol; air; sodium 35S-sulphate; pantothenic acid; D-myo-inositol; zinc diacetate; Thiamine hydrochloride; iron(III) chloride; DL-asparagine monohydrate; citric acid; sodium chloride; copper dichloride; magnesium chloride; biotin; at 30 ℃; for 24h; baker's yeast Saccharomyces cerevisiae;

DOI:10.1002/jlcr.2580340612

upstream raw materials:

D-Glucose

Refernces