3-(1-(4-Chlorobenzyl)-5-fluoro-3-methylindol-2-yl)-2,2-dimethylpropanoic acid

Base Information

Chemical Name:3-(1-(4-Chlorobenzyl)-5-fluoro-3-methylindol-2-yl)-2,2-dimethylpropanoic acid
CAS No.:103253-15-2
Molecular Formula:C₂₁H₂₁ClFNO₂
Molecular Weight:373.855
Hs Code.:
European Community (EC) Number:634-409-6
DSSTox Substance ID:DTXSID80908272
Nikkaji Number:J325.985D
Wikidata:Q27165258
ChEMBL ID:CHEMBL362223
Mol file:103253-15-2.mol

Synonyms:3-(1-(4-chlorobenzyl)-5-fluoro-3-methylindol-2-yl)-2,2-dimethylpropanoic acid;L 655240;L 655240 sodium;L-655240

Suppliers and Price of 3-(1-(4-Chlorobenzyl)-5-fluoro-3-methylindol-2-yl)-2,2-dimethylpropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
L-655,240
10mg
$ 423.00

TRC
L-655,240
2.5mg
$ 95.00

TRC
L-655,240
1mg
$ 45.00

Cayman Chemical
L-655,240 ≥98%
25mg
$ 840.00

Cayman Chemical
L-655,240 ≥98%
5mg
$ 216.00

Cayman Chemical
L-655,240 ≥98%
10mg
$ 384.00

Cayman Chemical
L-655,240 ≥98%
1mg
$ 48.00

ApexBio Technology
L-655,240
1mg
$ 67.00

ApexBio Technology
L-655,240
5mg
$ 299.00

ApexBio Technology
L-655,240
10mg
$ 532.00

Total 4 raw suppliers

Chemical Property of 3-(1-(4-Chlorobenzyl)-5-fluoro-3-methylindol-2-yl)-2,2-dimethylpropanoic acid

Chemical Property:

Vapor Pressure:7.1E-13mmHg at 25°C
Boiling Point:548.7°Cat760mmHg
PKA:4.82±0.10(Predicted)
Flash Point:285.7°C
PSA：42.23000
Density:1.22g/cm³
LogP:5.44380
Storage Temp.:Store at RT
Solubility.:DMSO: 30 mg/mL
XLogP3:5.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:373.1244848
Heavy Atom Count:26
Complexity:506

Purity/Quality:

≥98% ^*data from raw suppliers

L-655,240 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N(C2=C1C=C(C=C2)F)CC3=CC=C(C=C3)Cl)CC(C)(C)C(=O)O
Uses L-655,240 is a selective and potent thromboxane and prostaglandin endoperoxide antagonist. Also used in the structure-based and ligand-based drug design for microsomal prostaglandins E synthase-1 inhibitors.

Technology Process of 3-(1-(4-Chlorobenzyl)-5-fluoro-3-methylindol-2-yl)-2,2-dimethylpropanoic acid

There total 1 articles about 3-(1-(4-Chlorobenzyl)-5-fluoro-3-methylindol-2-yl)-2,2-dimethylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: