2-[4-(4-Methoxy-α-phenylphenethyl)phenoxy]ethyldiethylamine

Base Information

Chemical Name:2-[4-(4-Methoxy-α-phenylphenethyl)phenoxy]ethyldiethylamine
CAS No.:6732-77-0
Molecular Formula:C27H33NO2
Molecular Weight:403.61
Hs Code.:2922299090
Mol file:6732-77-0.mol

Synonyms:N,N-Diethyl-2-(4-(2-(4-methoxyphenyl)-1-phenylethyl)phenoxy)ethanamine;Mrl-37;

Suppliers and Price of 2-[4-(4-Methoxy-α-phenylphenethyl)phenoxy]ethyldiethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

2-(p-(p-METHOXY-α-PHENYLPHENETHYL)-PHENOXY)TRIETHYLAMINE" href="//zhangyi.lookchem.com/products/CasNo-6732-77-0--span-xmlns-style-font-weight-bold-2--p--p-METHOXY--span-alpha--PHENYLPHENETHYL--PHENOXY-TRIETHYLAMINE-28291304.html">
2-(p-(p-METHOXY-α-PHENYLPHENETHYL)-PHENOXY)TRIETHYLAMINE" href="//antimex.lookchem.com/products/CasNo-6732-77-0--span-xmlns-style-font-weight-bold-2--p--p-METHOXY--span-alpha--PHENYLPHENETHYL--PHENOXY-TRIETHYLAMINE-27239834.html">

Chemical Property of 2-[4-(4-Methoxy-α-phenylphenethyl)phenoxy]ethyldiethylamine

Chemical Property:

Vapor Pressure:3.76E-10mmHg at 25°C
Refractive Index:1.6400 (estimate)
Boiling Point:500.6°Cat760mmHg
Flash Point:136.5°C
PSA：21.70000
Density:1.049g/cm³
LogP:5.79040

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-[4-(4-Methoxy-α-phenylphenethyl)phenoxy]ethyldiethylamine

There total 7 articles about 2-[4-(4-Methoxy-α-phenylphenethyl)phenoxy]ethyldiethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 109-89-7
diethylamine

: 212759-38-1
1-<4-(2-bromoethoxy)phenyl>-1-phenyl-2-<4-methoxyphenyl>ethane

: 6732-77-0
1-<4-(2-dietylaminoethoxy)phenyl>-1-phenyl-2-<4-methoxyphenyl>ethane

Guidance literature:: With diethylamine; In chloroform; isopropyl alcohol; acetonitrile; at 40 ℃; for 16h;
DOI:10.1006/bioo.1998.1081

Reference yield:

: 589-10-6
phenoxyethyl bromide

: 6732-77-0
1-<4-(2-dietylaminoethoxy)phenyl>-1-phenyl-2-<4-methoxyphenyl>ethane

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) TFAA / 1.) RT, 2.) 20 deg C, 16 h

2: tetrahydrofuran; diethyl ether / 40 h / Heating

3: p-TsOH / benzene / 16 h / Heating

4: 42 percent / H₂ / 10 percent Pd/C / tetrahydrofuran / 18 h / Ambient temperature

5: 77 percent / Et₂NH / CHCl₃; acetonitrile; propan-2-ol / 16 h / 40 °C

With hydrogen; toluene-4-sulfonic acid; diethylamine; trifluoroacetic anhydride; palladium on activated charcoal; In tetrahydrofuran; diethyl ether; chloroform; isopropyl alcohol; acetonitrile; benzene;
DOI:10.1006/bioo.1998.1081

Reference yield:

: 212759-27-8
4-bromoethoxy-4'-methoxybenzyl ketone

: 6732-77-0
1-<4-(2-dietylaminoethoxy)phenyl>-1-phenyl-2-<4-methoxyphenyl>ethane

Guidance literature:: Multi-step reaction with 4 steps

1: tetrahydrofuran; diethyl ether / 40 h / Heating

2: p-TsOH / benzene / 16 h / Heating

3: 42 percent / H₂ / 10 percent Pd/C / tetrahydrofuran / 18 h / Ambient temperature

4: 77 percent / Et₂NH / CHCl₃; acetonitrile; propan-2-ol / 16 h / 40 °C

With hydrogen; toluene-4-sulfonic acid; diethylamine; palladium on activated charcoal; In tetrahydrofuran; diethyl ether; chloroform; isopropyl alcohol; acetonitrile; benzene;
DOI:10.1006/bioo.1998.1081