3-(o-Tolyloxy)-1,2-propanediol diacetate

Base Information

Chemical Name:3-(o-Tolyloxy)-1,2-propanediol diacetate
CAS No.:63991-86-6
Molecular Formula:C14H18 O5
Molecular Weight:266.294
Hs Code.:
DSSTox Substance ID:DTXSID80981843
Nikkaji Number:J90.352C

Synonyms:3-(o-Tolyloxy)-1,2-propanediol diacetate;63991-86-6;1,2-Propanediol, 3-(o-tolyloxy)-, diacetate;1-Tolyl ether-2,3-diacetate glycerol;3-(2-methylphenoxy)propane-1,2-diyl diacetate;DTXSID80981843

Suppliers and Price of 3-(o-Tolyloxy)-1,2-propanediol diacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-(O-TOLYLOXY)-1,2-PROPANEDIOL DIACETATE 95.00%
5MG
$ 498.82

Total 3 raw suppliers

Chemical Property of 3-(o-Tolyloxy)-1,2-propanediol diacetate

Chemical Property:

Vapor Pressure:6.85E-06mmHg at 25°C
Boiling Point:377.2°Cat760mmHg
Flash Point:165.5°C
PSA：61.83000
Density:1.127g/cm³
LogP:1.86860
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:266.11542367
Heavy Atom Count:19
Complexity:302

Purity/Quality:

99% ^*data from raw suppliers

3-(O-TOLYLOXY)-1,2-PROPANEDIOL DIACETATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1OCC(COC(=O)C)OC(=O)C

Technology Process of 3-(o-Tolyloxy)-1,2-propanediol diacetate

There total 6 articles about 3-(o-Tolyloxy)-1,2-propanediol diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-05-4,9003-20-7
vinyl acetate

: 59-47-2
mephenesin

: 138710-05-1,105476-17-3
1-acetoxy-3-(2-methylphenoxy)propan-2-ol

: 63991-86-6,138710-06-2
Acetic acid (R)-1-acetoxymethyl-2-o-tolyloxy-ethyl ester

: 138710-06-2
Acetic acid (S)-1-acetoxymethyl-2-o-tolyloxy-ethyl ester

Guidance literature:: With triethylamine; In various solvent(s); for 60h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; lipase amano PS;
DOI:10.1021/jo00081a018

Reference yield:

: 108-05-4,9003-20-7
vinyl acetate

: 59-47-2
mephenesin

: 153497-92-8
(S)-1-acetoxy-3-(2-methylphenoxy)propan-2-ol

: 138710-05-1
(R)-1-acetoxy-3-(2-methylphenoxy)propan-2-ol

: 63991-86-6
Acetic acid 1-acetoxymethyl-2-o-tolyloxy-ethyl ester

Guidance literature:: With triethylamine; In tetrahydrofuran; for 96h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; lipase amano PS;
DOI:10.1021/jo00081a018

Reference yield:

: 25772-91-2
1-chloro-3-(2-methylphenoxy)propan-2-ol

: 63991-86-6
Acetic acid 1-acetoxymethyl-2-o-tolyloxy-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 231 mg / NaH / ethyl acetate; hexane / 0.08 h

2: 100 - 110 °C

With sodium hydride; In hexane; ethyl acetate; 1: Cyclization / 2: Acetoxylation;
DOI:10.1002/(SICI)1099-1344(200002)43:2<147::AID-JLCR301>3.0.CO;2-H