10,11-Dihydro-10,11-dihydroxy Protriptyline

Base Information

• Chemical Name: 10,11-Dihydro-10,11-dihydroxy Protriptyline
• CAS No.: 29785-65-7
• Molecular Formula: C₁₉H₂₃NO₂
• Molecular Weight: 297.397
• Mol file: 29785-65-7.mol

Synonyms:10,11-Dihydro-10,11-dihydroxyprotriptyline;10,11-Dihydroxy-N-methyl-5H-dibenzo[a,d]cycloheptane-5-propylamine

Chemical Property of 10,11-Dihydro-10,11-dihydroxy Protriptyline

Chemical Property:

• PSA: 52.49000
• LogP: 3.28940

Purity/Quality:

97% ^*data from raw suppliers

10,11-Dihydro-10,11-dihydroxyProtriptyline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite of Protriptyline.

Technology Process of 10,11-Dihydro-10,11-dihydroxy Protriptyline

There total 3 articles about 10,11-Dihydro-10,11-dihydroxy Protriptyline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Protriptylin (438-60-8) → 10-Hydroxyprotriptyline (27462-57-3) + 10,11-Dihydroprotriptyline diol (29785-65-7)

Guidance literature:

With formic acid; dihydrogen peroxide; 1.) 40 deg C, 1 h, 2.) 20 deg C, 16 h;

DOI:10.1111/j.2042-7158.1984.tb02986.x

Reference yield:

protriptyline hydrochloride (1225-55-4) → Protriptyline 10,11-epoxide (55698-64-1) + 10-Hydroxyprotriptyline (27462-57-3) + 10,11-Dihydroprotriptyline diol (29785-65-7)

Guidance literature:

With oxygen; In water; for 16h; Irradiation;

DOI:10.1111/j.2042-7158.1984.tb02986.x

Reference yield:

→ 10,11-Dihydroprotriptyline diol (29785-65-7)

Guidance literature:

Protriptlin*HCl (s.F.I), OsO4, Stoffwechselprodukt;

upstream raw materials:

Protriptylin

protriptyline hydrochloride

Refernces