Conocarpin

Base Information

Chemical Name:Conocarpin
CAS No.:14225-07-1
Molecular Formula:C₁₅H₁₆O₈
Molecular Weight:324.287
Hs Code.:
NSC Number:112845
DSSTox Substance ID:DTXSID90296955
Wikidata:Q105135600
ChEMBL ID:CHEMBL1964970
Mol file:14225-07-1.mol

Synonyms:Conocarpin;1,7-Dioxaspiro[4.4]nonane-2,6-dione, 8-(1,2-dihydroxyethyl)-9-hydroxy-4-(4-hydroxyphenyl)-, [5S-[5.alpha.(R*),8.alpha.(R*),9.beta.]]-;CHEMBL1964970;DTXSID90296955;JVCLQSJXGOABTC-UHFFFAOYSA-N;NSC112845;NCI60_000285;1,6-dione, 8-(1,2-dihydroxyethyl)-9-hydroxy-4-(p-hydroxyphenyl)-;1,6-dione, 8-(1,2-dihydroxyethyl)-9-hydroxy-4-(4-hydroxyphenyl)-, [5S-[5.alpha.(S*),8.alpha.(R*),9.beta.]]-;1,7-Dioxaspiro[4.4]nonane-2,6-dione,8-[(1S)- 1,2-dihydroxyethyl]-9-hydroxy-4-(4-hydroxyphenyl)-,(4S,5S,8R,9R)-;8-(1,2-Dihydroxyethyl)-9-hydroxy-4-(4-hydroxyphenyl)-1,7-dioxaspiro[4.4]nonane-2,6-dione-, (4S,5S,8R,9R)-

Suppliers and Price of Conocarpin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Conocarpin

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:212-212.5°
Boiling Point:747.73°C at 760 mmHg
Flash Point:282.678°C
PSA：133.52000
Density:1.632g/cm³
LogP:-1.19900
XLogP3:-0.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:324.08451746
Heavy Atom Count:23
Complexity:486

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C2(C(C(OC2=O)C(CO)O)O)OC1=O)C3=CC=C(C=C3)O

Technology Process of Conocarpin

There total 8 articles about Conocarpin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 113119-31-6
aglycone of dilaspirolactone

: 14225-07-1,30358-74-8,35739-81-2
leucodrin

Guidance literature:: With diborane; In tetrahydrofuran; for 1h; Heating;
DOI:10.1021/jo00242a037

Reference yield: 69.0%

: 113119-31-6
aglycone of dilaspirolactone

: 14225-07-1,30358-74-8,35739-81-2
(4R,5S,8R,9R)-8-((R)-1,2-Dihydroxy-ethyl)-9-hydroxy-4-(4-hydroxy-phenyl)-1,7-dioxa-spiro[4.4]nonane-2,6-dione

Guidance literature:: With diborane; In tetrahydrofuran; for 1h; Heating;
DOI:10.1016/S0040-4039(00)96146-X

Reference yield:

: leucodrin

: 14225-07-1,30358-74-8,35739-81-2
leucodrin

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In tetrahydrofuran; ethyl acetate; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1039/c3ob00046j