Clorgiline

Base Information

Chemical Name:Clorgiline
CAS No.:17780-72-2
Molecular Formula:C13H15 Cl2 N O
Molecular Weight:272.174
Hs Code.:2922299090
UNII:LYJ16FZU9Q
DSSTox Substance ID:DTXSID3048445
Nikkaji Number:J10.191E
Wikipedia:Clorgiline
Wikidata:Q2889652
NCI Thesaurus Code:C77522
Pharos Ligand ID:WDZF3J4AC5C6
Metabolomics Workbench ID:53081
ChEMBL ID:CHEMBL8706
Mol file:17780-72-2.mol

Synonyms:Chlorgyline;Clorgilin;Clorgiline;Clorgyline

Suppliers and Price of Clorgiline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
CLORGILINE 95.00%
5MG
$ 504.22

Total 13 raw suppliers

Chemical Property of Clorgiline

Chemical Property:

Vapor Pressure:2.1E-05mmHg at 25°C
Boiling Point:361.3°Cat760mmHg
Flash Point:172.3°C
PSA：12.47000
Density:1.196g/cm³
LogP:3.32730
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:271.0530695
Heavy Atom Count:17
Complexity:263

Purity/Quality:

99% ^*data from raw suppliers

CLORGILINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(CCCOC1=C(C=C(C=C1)Cl)Cl)CC#C

Technology Process of Clorgiline

There total 8 articles about Clorgiline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 85507-24-0
N-methyl-3-(2,4-dichlorophenoxy)propylamine

: 106-96-7
propargyl bromide

: 17780-72-2
clorgyline

Guidance literature:: With potassium carbonate; In dichloromethane; at 0 - 25 ℃; Inert atmosphere; Schlenk technique;
DOI:10.1002/anie.201712618

Reference yield:

: 62505-89-9
5-{[3-(2,4-Dichloro-phenoxy)-propyl]-methyl-amino}-2-methyl-pent-3-yn-2-ol

: 17780-72-2
clorgyline

Guidance literature:: With potassium hydroxide; at 150 ℃; under 1 Torr;
DOI:10.1021/jo00435a026

Reference yield:

: 120-83-2,40477-79-0
2,4-dichlorophenol

: 17780-72-2
clorgyline

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / 3 h / Heating

2: potassium carbonate / acetonitrile; H₂O / 48 h / Ambient temperature

With sodium hydroxide; potassium carbonate; In water; acetonitrile;
DOI:10.1248/cpb.39.1038