Pyridazine-3-carboxylic acid aMide

Base Information

• Chemical Name: Pyridazine-3-carboxylic acid aMide
• CAS No.: 5450-54-4
• Molecular Formula: C5H5N3O
• Molecular Weight: 123.114
• Hs Code.: 2933990090
• Mol file: 5450-54-4.mol

Synonyms:Pyridazin-3-carbamid;Pyridazine-3-carboxyamide;3-Carbamoyl-pyridazin;Pyridazine-3-carboxylic acid amide;PYRIDAZINECARBOXAMIDE;3-Pyridazinecarboxamide;

Chemical Property of Pyridazine-3-carboxylic acid aMide

Chemical Property:

• Vapor Pressure: 2.36E-08mmHg at 25°C
• Boiling Point: 451.8°Cat760mmHg
• Flash Point: 227.1°C
• PSA: 68.87000
• Density: 1.301g/cm³
• LogP: 0.27580

Purity/Quality:

97% ^*data from raw suppliers

Pyridazine-3-carboxylicacidamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyridazine-3-carboxylic acid aMide

There total 6 articles about Pyridazine-3-carboxylic acid aMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

pyridazine-3-carbonitrile (53896-49-4) → Pyridazine-3-carboxyamide (5450-54-4)

Guidance literature:

With [RuCl₂(η³:η³-2,7-dimethylocta-2,6-diene-1,8-diyl)(PMe₂OH)]; In water; at 60 ℃; for 8h; Catalytic behavior; Inert atmosphere; Sealed tube;

DOI:10.1039/c6dt02375d

Reference yield: 80.0%

Methyl pyridazine-3-carboxylate (34253-02-6) → Pyridazine-3-carboxyamide (5450-54-4)

Guidance literature:

With ammonia; In tetrahydrofuran; at 50 ℃; for 12h; Inert atmosphere;

Reference yield: 58.0%

pyridazine-3-carbonyl chloride (499770-82-0) → Pyridazine-3-carboxyamide (5450-54-4)

Guidance literature:

With ammonium hydroxide; In tetrahydrofuran; at 25 ℃; for 1h; Inert atmosphere;

upstream raw materials:

Methyl pyridazine-3-carboxylate

ethyl 3-pyridazinecarboxylate

pyridazine-3-carbonitrile

pyridazine-3-carboxylic acid

Downstream raw materials:

3-Oximinoaminomethyl-pyridazin

N-phenyl-pyridazine-3-carboximidic acid amide