N-methylammodendrine

Base Information

Chemical Name:N-methylammodendrine
CAS No.:52196-10-8
Molecular Formula:C13H22N2O
Molecular Weight:222.3266
Hs Code.:
Mol file:52196-10-8.mol

Synonyms:1'-acetyl-1-methyl-1,2,3,4,5,6,1',4',5',6'-decahydro-[2,3']bipyridinyl;N'-Methylammodendrin;N`-Methylammodendrine;1-(1-Methyl-1,2,3,4,5,6,5',6'-octahydro-4'H-[2,3']bipyridinyl-1'-yl)-ethanone;N'-Methylammodendrine;N-Methylammodendrin;(+-)-1'-Acetyl-1-methyl-1,2,3,4,5,6,1',4',5',6'-decahydro-[2,3']bipyridyl;

Suppliers and Price of N-methylammodendrine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of N-methylammodendrine

Chemical Property:

Vapor Pressure:1.96E-05mmHg at 25°C
Boiling Point:362.2°Cat760mmHg
Flash Point:153.7°C
PSA：23.55000
Density:1.052g/cm³
LogP:1.87270

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-methylammodendrine

There total 6 articles about N-methylammodendrine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

: 494-15-5,27542-15-0,54966-22-2
(+)-ammodendrine

: 74-88-4
methyl iodide

: 52196-10-8,119157-64-1
N-methylammodendrine

Guidance literature:: In acetone; at 57 ℃; for 1h;
DOI:10.1021/np0580199

Reference yield:

: 852922-11-3
L-Ala-D-ammodendrine

: 52196-10-8,119157-64-1
N-methylammodendrine

Guidance literature:: Multi-step reaction with 2 steps

1.1: aq. Et₃N; phenylisothiocyanate / methanol / 1.5 h / 50 °C

1.2: TFA / methanol / 1.5 h / 50 °C

2.1: 29 percent / acetone / 1 h / 57 °C

With phenyl isothiocyanate; triethylamine; In methanol; acetone; 1.1: Edman degradation;
DOI:10.1021/np0580199

Reference yield:

: 852922-10-2
Fmoc-L-Ala-ammodendrine

: 52196-10-8,119157-64-1
N-methylammodendrine

Guidance literature:: Multi-step reaction with 3 steps

1.1: piperidine / CH₂Cl₂ / 1 h / 20 °C

2.1: aq. Et₃N; phenylisothiocyanate / methanol / 1.5 h / 50 °C

2.2: TFA / methanol / 1.5 h / 50 °C

3.1: 29 percent / acetone / 1 h / 57 °C

With piperidine; phenyl isothiocyanate; triethylamine; In methanol; dichloromethane; acetone; 2.1: Edman degradation;
DOI:10.1021/np0580199