3,6-Dichloro-2-methoxyphenol

Base Information

• Chemical Name: 3,6-Dichloro-2-methoxyphenol
• CAS No.: 77102-93-3
• Molecular Formula: C₇H₆Cl₂O₂
• Molecular Weight: 193.029
• Hs Code.: 2909500000
• DSSTox Substance ID: DTXSID20227893
• Nikkaji Number: J1.591.142E
• Wikidata: Q83107730
• Mol file: 77102-93-3.mol

Synonyms:3,6-Dichloro-2-methoxyphenol;77102-93-3;2-Methoxy-3,6-dichloro-phenol;Phenol,3,6-dichloro-2-methoxy-;Phenol, 3,6-dichloro-2-methoxy-;3,6-dichloroguaiacol;2-methoxy-3,6-dichlorophenol;2,5-Dichloro-6-methoxyphenol;SCHEMBL9332617;DTXSID20227893;3,6-Dichloro-2-methoxyphenol #;3,6-bis(chloranyl)-2-methoxy-phenol;EN300-6812434;A840146

Chemical Property of 3,6-Dichloro-2-methoxyphenol

Chemical Property:

• Vapor Pressure: 0.0174mmHg at 25°C
• Boiling Point: 246.3°C at 760 mmHg
• Flash Point: 102.8°C
• PSA: 29.46000
• Density: 1.421g/cm³
• LogP: 2.70760
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 191.9744848
• Heavy Atom Count: 11
• Complexity: 132

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=CC(=C1O)Cl)Cl

Technology Process of 3,6-Dichloro-2-methoxyphenol

There total 1 articles about 3,6-Dichloro-2-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-dichloro-2,3-dihydroxybenzene (3938-16-7) + dimethyl sulfate (77-78-1) → 3,6-Dichloro-2-methoxyphenol (77102-93-3)

Guidance literature:

With sodium hydroxide; Yield given. Multistep reaction; 1.) 20 deg C, 15 min., 20 deg C, 15 min.;

DOI:10.1021/je00025a040

Reference yield:

3,6-Dichloro-2-methoxyphenol (77102-93-3) → 3,4,6-trichloroguaiacol (60712-44-9)

Guidance literature:

With sulfuryl dichloride; In chloroform;

DOI:10.1002/oms.1210190210

Reference yield:

iodomethane-d3 (865-50-9) + 3,6-Dichloro-2-methoxyphenol (77102-93-3) → C8H5(2)H3Cl2O2

Guidance literature:

With deuteriated sodium hydroxide; water-d2; In acetone;

DOI:10.1002/oms.1210241022

upstream raw materials:

1,4-dichloro-2,3-dihydroxybenzene

dimethyl sulfate

Downstream raw materials:

3,4,6-trichloroguaiacol