Technology Process of 1,2-Cyclooctanedione, 3-(phenylmethoxy)-
There total 5 articles about 1,2-Cyclooctanedione, 3-(phenylmethoxy)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Dess-Martin periodane;
In
dichloromethane;
at 20 ℃;
for 2h;
DOI:10.1021/jo0358675
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 97 percent / hydrogen / palladium on carbon / ethanol / 3.17 h / 760 Torr
2.1: 82 percent / Tf2O / diethyl ether
3.1: lithium hexamethyldisilazide / tetrahydrofuran / 1 h / -78 °C
3.2: chlorotrimethylsilane / tetrahydrofuran / 20 °C
3.3: 50 percent / oxone; NaHCO3 / H2O; acetone / 0 - 20 °C
4.1: 99 percent / Dess-Martin periodinane / CH2Cl2 / 2 h / 20 °C
With
trifluoromethylsulfonic anhydride; hydrogen; Dess-Martin periodane; lithium hexamethyldisilazane;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; ethanol; dichloromethane;
DOI:10.1021/jo0358675
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: CF3SO3H / diethyl ether
2.1: LHMDS / tetrahydrofuran / -78 °C
2.2: 50 percent / TMSCl; oxone; aq. NaHCO3 / acetone
3.1: 99 percent / Dess-Martin periodinane
With
trifluorormethanesulfonic acid; Dess-Martin periodane; lithium hexamethyldisilazane;
In
tetrahydrofuran; diethyl ether;
