Technology Process of 1,2-Cyclooctanedione, 3-(phenylmethoxy)-
There total 5 articles about 1,2-Cyclooctanedione, 3-(phenylmethoxy)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
Dess-Martin periodane;
In
dichloromethane;
at 20 ℃;
for 2h;
DOI:10.1021/jo0358675
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 97 percent / hydrogen / palladium on carbon / ethanol / 3.17 h / 760 Torr
2.1: 82 percent / Tf2O / diethyl ether
3.1: lithium hexamethyldisilazide / tetrahydrofuran / 1 h / -78 °C
3.2: chlorotrimethylsilane / tetrahydrofuran / 20 °C
3.3: 50 percent / oxone; NaHCO3 / H2O; acetone / 0 - 20 °C
4.1: 99 percent / Dess-Martin periodinane / CH2Cl2 / 2 h / 20 °C
With
trifluoromethylsulfonic anhydride; hydrogen; Dess-Martin periodane; lithium hexamethyldisilazane;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; ethanol; dichloromethane;
DOI:10.1021/jo0358675
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: CF3SO3H / diethyl ether
2.1: LHMDS / tetrahydrofuran / -78 °C
2.2: 50 percent / TMSCl; oxone; aq. NaHCO3 / acetone
3.1: 99 percent / Dess-Martin periodinane
With
trifluorormethanesulfonic acid; Dess-Martin periodane; lithium hexamethyldisilazane;
In
tetrahydrofuran; diethyl ether;