2-(4-(2-(Diethylamino)ethoxy)phenyl)-3-(4-(trifluoromethyl)phenyl)acrylonitrile

Base Information

Chemical Name:2-(4-(2-(Diethylamino)ethoxy)phenyl)-3-(4-(trifluoromethyl)phenyl)acrylonitrile
CAS No.:1174-06-7
Molecular Formula:C₂₂H₂₃F₃N₂O
Molecular Weight:388.433
Hs Code.:
UNII:SF2HQ46X8V

Synonyms:NSC59474;SF2HQ46X8V;1174-06-7;NSC 59474;NSC-59474;UNII-SF2HQ46X8V;2-(4-(2-(Diethylamino)ethoxy)phenyl)-3-(4-(trifluoromethyl)phenyl)acrylonitrile;(E)-2-[4-(2-diethylaminoethyloxy)phenyl]-3-[4-(trifluoromethyl)phenyl]prop-2-enenitrile;(E)-2-(4-(2-(DIETHYLAMINO)ETHOXY)PHENYL)-3-(4-(TRIFLUOROMETHYL)PHENYL)PROP-2-ENENITRILE;4-(2-(DIETHYLAMINO)ETHOXY)-.ALPHA.-((4-(TRIFLUOROMETHYL)PHENYL)METHYLENE)BENZENEACETONITRILE;BENZENEACETONITRILE, 4-(2-(DIETHYLAMINO)ETHOXY)-.ALPHA.-((4-(TRIFLUOROMETHYL)PHENYL)METHYLENE)-

Suppliers and Price of 2-(4-(2-(Diethylamino)ethoxy)phenyl)-3-(4-(trifluoromethyl)phenyl)acrylonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2-(4-(2-(Diethylamino)ethoxy)phenyl)-3-(4-(trifluoromethyl)phenyl)acrylonitrile

Chemical Property:

Vapor Pressure:6.62E-09mmHg at 25°C
Boiling Point:467.2°Cat760mmHg
Flash Point:236.4°C
Density:1.165g/cm³
XLogP3:5.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:388.17624785
Heavy Atom Count:28
Complexity:532

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CCOC1=CC=C(C=C1)C(=CC2=CC=C(C=C2)C(F)(F)F)C#N
Isomeric SMILES:CCN(CC)CCOC1=CC=C(C=C1)/C(=C\C2=CC=C(C=C2)C(F)(F)F)/C#N

Technology Process of 2-(4-(2-(Diethylamino)ethoxy)phenyl)-3-(4-(trifluoromethyl)phenyl)acrylonitrile

There total 4 articles about 2-(4-(2-(Diethylamino)ethoxy)phenyl)-3-(4-(trifluoromethyl)phenyl)acrylonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14191-95-8
4-cyanomethylphenol

: 1174-06-7
2-<4-(2-Diaethylamino-aethoxy)-phenyl>-3-<4-trifluor-methyl-phenyl>-acrylnitril

Guidance literature:: Multi-step reaction with 2 steps

1: NaOEt, EtOH

2: NaOMe, MeOH

With methanol; ethanol; sodium methylate; sodium ethanolate;
DOI:10.1021/jm00334a025

Reference yield:

: 104-47-2
p-methoxybenzylnitrile

: 1174-06-7
2-<4-(2-Diaethylamino-aethoxy)-phenyl>-3-<4-trifluor-methyl-phenyl>-acrylnitril

Guidance literature:: Multi-step reaction with 3 steps

1: Py*HCl

2: NaOEt, EtOH

3: NaOMe, MeOH

With methanol; ethanol; sodium methylate; sodium ethanolate; pyridine hydrochloride;
DOI:10.1021/jm00334a025