2-Chloro-3-(piperazin-1-yl)pyrazine hydrochloride

Base Information

• Chemical Name: 2-Chloro-3-(piperazin-1-yl)pyrazine hydrochloride
• CAS No.: 66522-30-3
• Molecular Formula: C₈H₁₁ClN₄*2ClH
• Molecular Weight: 271.577
• Mol file: 66522-30-3.mol

Synonyms:Pyrazine, 2-chloro-3-(1-piperazinyl)-, monohydrochloride (9CI);Pyrazine, 2-chloro-3-(1-piperazinyl)-, hydrochloride (1:1);

Chemical Property of 2-Chloro-3-(piperazin-1-yl)pyrazine hydrochloride

Chemical Property:

• PSA: 41.05000
• LogP: 1.73540
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-3-(piperazin-1-yl)pyrazineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Chloro-3-(piperazin-1-yl)pyrazine hydrochloride

There total 1 articles about 2-Chloro-3-(piperazin-1-yl)pyrazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-Chloro-3-(4-tert-butoxycarbonyl-1-piperazinyl)pyrazine (313654-83-0) → 3'-chloro-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl dihydrochloride (66522-30-3)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 3h;

upstream raw materials:

2-Chloro-3-(4-tert-butoxycarbonyl-1-piperazinyl)pyrazine

Refernces