diallyl sulfone

Base Information

• Chemical Name: diallyl sulfone
• CAS No.: 16841-48-8
• Molecular Formula: C6H10 O2 S
• Molecular Weight: 146.21
• Hs Code.: 2904100000
• Mol file: 16841-48-8.mol

Synonyms:1-Propene,3,3'-sulfonylbis- (9CI); Allyl sulfone (6CI,7CI,8CI); Bis(allyl) sulfone;Diallyl sulfone; NSC 10979

Chemical Property of diallyl sulfone

Chemical Property:

• Vapor Pressure: 0.0192mmHg at 25°C
• Refractive Index: 1.4893 (estimate)
• Boiling Point: 261°Cat760mmHg
• Flash Point: 125°C
• PSA: 42.52000
• Density: 1.053g/cm³
• LogP: 1.85400

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of diallyl sulfone

There total 2 articles about diallyl sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-tolyl iodide (624-31-7) + allyltrimethoxysilane (2551-83-9) → diallyl sulfone (16841-48-8) + 1-methyl-4-(prop-2-ene-1-sulfonyl)benzene (3112-87-6)

Guidance literature:

4-tolyl iodide; allyltrimethoxysilane; With palladium(II) acetylacetonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tetrabutylammonium triphenyldifluorosilicate; In tetrahydrofuran; Glovebox;

With potassium pyrosulfite; at 600 ℃; Glovebox; Inert atmosphere;

In tetrahydrofuran; at 20 - 80 ℃; for 4h; regioselective reaction; Glovebox;

DOI:10.1039/c9cc06858a

Reference yield:

4-tolyl iodide (624-31-7) + allyl(methoxy)dimethylsilane (30535-30-9) → diallyl sulfone (16841-48-8) + 1-methyl-4-(prop-2-ene-1-sulfonyl)benzene (3112-87-6)

Guidance literature:

4-tolyl iodide; allyl(methoxy)dimethylsilane; With palladium(II) acetylacetonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tetrabutylammonium triphenyldifluorosilicate; In tetrahydrofuran; Glovebox;

With potassium pyrosulfite; at 600 ℃; Glovebox; Inert atmosphere;

In tetrahydrofuran; at 20 - 80 ℃; for 4h; regioselective reaction; Glovebox;

DOI:10.1039/c9cc06858a

Reference yield: 98.0%

diallyl sulfone (16841-48-8) → 3-Sulfolene (77-79-2)

Guidance literature:

With C₃₄H₄₃Cl₂N₃O₂Ru; In dichloromethane; at 35 ℃; for 0.5h; Inert atmosphere;

DOI:10.1016/j.poly.2014.03.034

upstream raw materials:

4-tolyl iodide

allyltrimethoxysilane

allyl(methoxy)dimethylsilane

Downstream raw materials:

propyl sulfone

2,6-dimethyl-[1,4]oxathiane-4,4-dioxide

1-<2-(4-Hydroxyphenyl)ethyl>-2,6-dimethyl-4,1-thiazane 4,4-dioxide

2-iodo-1,3-bis(p-tolylsulphonyl)propane

Refernces

An improved convergent strategy for the synthesis of oligoprenols

10.1002/hlca.200890211

The present study aimed to develop a practical and highly regio- and stereoselective method for the synthesis of oligoisoprenols, essential precursors for the synthesis of biologically important isoprenoids. The convergent synthetic strategy described is characterized by iterative allyl-allyl couplings of monomers derived from commercially available geraniol and repeated reductive elimination of p-toluenesulfonyl (Ts) groups. The study successfully demonstrated the use of this approach to synthesize (all-trans)-oligoisoprenols, such as (all-trans)-octaprenol and (all-trans)-decaprenol, which is more efficient and practical compared to previous methods. The key chemicals used in the process include geraniol, p-toluenesulfonyl, allyl bromide, allyl sulfone, and various reducing agents such as Li/EtNH2, Na/EtOH, Na/naphthalene, and LiHBEt3/Pd(dppp)Cl2. The study concluded that the developed convergent strategy is an effective method for the synthesis of long linear polyprene backbones.

Chemistry of allylsulfones: A new preparation of N-diphenylmethylene-2- vinyl-substituted cyclopropylamines

10.1055/s-2004-835663

The study presents a novel methodology for synthesizing N-diphenylmethylene-2-vinyl-substituted cyclopropylamines, which are significant in pharmaceuticals and natural products due to their biological activity. The synthesis begins with allylsulfones, specifically compound 11, which can be obtained in both enantiomeric forms. The researchers utilized various chemicals, including base treatments for allylsulfones to form trans:cis cyclopropanols, and molecular modeling to study the stereoselectivity of cyclopropane formation. The study also involved the use of Garner’s aldehyde, a key intermediate in synthesizing biologically active compounds, and the transformation of amino alcohols into cyclopropylamines with the help of protecting groups like Tosyl, Boc, Moc, and benzyl. The purpose of these chemicals was to achieve high diastereoselectivity in the synthesis of chiral amino-cyclopropanes, which are valuable as building blocks for the synthesis of conformationally restricted amino acids. The study's innovative approach and findings contribute to the field of asymmetric synthesis, particularly for cyclopropylamines.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 16841-48-8 diallyl sulfone

Send

Send

Metric Ton KG G Pound L ML

Send

Send