1-Propanone,3,3-diphenyl-1-(2,4,6-trimethylphenyl)-

Base Information

• Chemical Name: 1-Propanone,3,3-diphenyl-1-(2,4,6-trimethylphenyl)-
• CAS No.: 55800-31-2
• Molecular Formula: C24H24O
• Molecular Weight: 328.454
• Mol file: 55800-31-2.mol

Synonyms:1.1-Diphenyl-3-(2.4.6-trimethyl-phenyl)-propanon-(3);γ-Oxo-α.α-diphenyl-γ-(2.4.6-trimethyl-phenyl)-propan;1-Mesityl-3,3-diphenyl-propan-1-on;2.4.6-Trimethyl-β.β-diphenyl-propiophenon;1-mesityl-3,3-diphenyl-propan-1-one;Kohler's ketone;

Chemical Property of 1-Propanone,3,3-diphenyl-1-(2,4,6-trimethylphenyl)-

Chemical Property:

• PSA: 17.07000
• LogP: 6.01670

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Propanone,3,3-diphenyl-1-(2,4,6-trimethylphenyl)-

There total 14 articles about 1-Propanone,3,3-diphenyl-1-(2,4,6-trimethylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

1,1-Diphenylmethanol (91-01-0) + 2,4,6-Trimethylacetophenone (1667-01-2,51885-97-3) → 1-mesityl-3,3-diphenylpropan-1-one (55800-31-2)

Guidance literature:

With trimethylamine-N-oxide; (1,4-dimethyl-5,7-diphenyl-1,2,3,4-tetrahydro-6H-cyclopenta[b]pyrazin-6-one) irontricarbonyl complex3; sodium t-butanolate; In toluene; at 110 ℃; for 24h; chemoselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.0c00549

Reference yield:

diethyl ether (60-29-7,927820-24-4) + C24H23O(1-)*Br(1-)*Mg(2+) → Diphenylacetaldehyde (947-91-1) + biphenyl (92-52-4,1594-86-1) + 1-Phenylethanol (98-85-1,13323-81-4) + 1-mesityl-3,3-diphenylpropan-1-one (55800-31-2) + phenol (108-95-2,27073-41-2)

Guidance literature:

With oxygen; Product distribution; from 100 deg C to 250 deg C at rate 10 deg C/min;

DOI:10.1016/S0040-4020(01)86206-2

Reference yield:

→ 1-mesityl-3,3-diphenylpropan-1-one (55800-31-2)

Guidance literature:

With platinum; Hydrogenation;

DOI:10.1021/jo01182a011

upstream raw materials:

diethyl ether

3-phenyl-1-(2,4,6-trimethylphenyl)-2-propen-1-one

3,3-diphenylpropanoyl chloride

1,3,5-trimethyl-benzene

Downstream raw materials:

1t-benzoyloxy-1c-mesityl-3,3-diphenyl-propene

2-bromo-3,3-diphenyl-1-(2,4,6-trimethylphenyl)propan-1-one

3,3-diphenyl-2-hydroperoxy-1-(2,4,6-trimethylphenyl)propane-1-one

1-mesityl-3,3-diphenylprop-2-en-1-one