2-Methyl-3-(3-nitrophenyl)propanoic acid

Base Information

Chemical Name:2-Methyl-3-(3-nitrophenyl)propanoic acid
CAS No.:66735-02-2
Molecular Formula:C10H11NO4
Molecular Weight:209.202
Hs Code.:
DSSTox Substance ID:DTXSID201285461

Synonyms:2-methyl-3-(3-nitrophenyl)propanoic acid;66735-02-2;SCHEMBL10341513;DTXSID201285461;I+/--Methyl-3-nitrobenzenepropanoic acid;EN300-1829778

Suppliers and Price of 2-Methyl-3-(3-nitrophenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Methyl-3-(3-nitrophenyl)propanoic acid

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:209.06880783
Heavy Atom Count:15
Complexity:248

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CC1=CC(=CC=C1)[N+](=O)[O-])C(=O)O

Technology Process of 2-Methyl-3-(3-nitrophenyl)propanoic acid

There total 10 articles about 2-Methyl-3-(3-nitrophenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 66735-02-2
(+/-)-2-methyl-3-(3-nitro-phenyl)-propionic acid

Guidance literature:

Reference yield:

: 2-Methyl-2-(3-nitro-benzyl)-malonic acid

: 66735-02-2
(+/-)-2-methyl-3-(3-nitro-phenyl)-propionic acid

Guidance literature:: In N,N-dimethyl-formamide; at 100 - 110 ℃; for 4h;
DOI:10.1016/S0957-4166(00)86152-2

Reference yield:

: 2-Methyl-2-(3-nitro-benzyl)-malonic acid

: 66735-02-2,138711-97-4
(R)-2-(3-nitrobenzyl)propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: dimethylformamide / 4 h / 100 - 110 °C

2: HCl / 24 h / Ambient temperature

3: 0.1 M potassium phosphate / 6 h / Ambient temperature

With hydrogenchloride; potassium phosphate; In N,N-dimethyl-formamide;
DOI:10.1016/S0957-4166(00)86152-2