N-Phenethyl-N-tosylglycine

Base Information

Chemical Name:N-Phenethyl-N-tosylglycine
CAS No.:66895-91-8
Molecular Formula:C17H19NO4S
Molecular Weight:333.408
Hs Code.:
DSSTox Substance ID:DTXSID20353424
Nikkaji Number:J873.792D
Wikidata:Q82131016
ChEMBL ID:CHEMBL2010979

Synonyms:CHEMBL2010979;66895-91-8;ST50998517;Oprea1_506767;Oprea1_828514;SCHEMBL22469193;DTXSID20353424;BDBM50484941;AKOS000297250;EU-0009225;SR-01000472815;SR-01000472815-1

Suppliers and Price of N-Phenethyl-N-tosylglycine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of N-Phenethyl-N-tosylglycine

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:333.10347926
Heavy Atom Count:23
Complexity:471

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N(CCC2=CC=CC=C2)CC(=O)O

Technology Process of N-Phenethyl-N-tosylglycine

There total 7 articles about N-Phenethyl-N-tosylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 904246-40-8
N-(2-phenylethyl)-N-[(4-methylphenyl)sulfonyl]glycine methyl ester

: 66895-91-8
N-(2-phenylethyl)-N-[(4-methylphenyl)sulfonyl]glycine

Guidance literature:: N-(2-phenylethyl)-N-[(4-methylphenyl)sulfonyl]glycine methyl ester; With sodium hydroxide; In methanol; for 1h; Reflux;

With hydrogenchloride; In water; at 20 ℃; pH=2;
DOI:10.1016/j.ejmech.2012.02.045

Reference yield:

: ethyl N-phenethyl-N-tosylglycinate

: 66895-91-8
N-(2-phenylethyl)-N-[(4-methylphenyl)sulfonyl]glycine

Guidance literature:: With sodium hydroxide; In ethanol; water; at 50 ℃; for 3h;

Reference yield:

: 5450-75-9
4-methyl-N-(2-phenylethyl)benzenesulfonamide

: 66895-91-8
N-(2-phenylethyl)-N-[(4-methylphenyl)sulfonyl]glycine

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C

2.1: sodium hydroxide / methanol / 1 h / Reflux

2.2: 20 °C / pH 2

With potassium carbonate; sodium hydroxide; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2012.02.045