beta-(Hydroxymethoxy)tricarballylic acid gamma-lactone benzyl ester

Base Information

Chemical Name:beta-(Hydroxymethoxy)tricarballylic acid gamma-lactone benzyl ester
CAS No.:109100-88-1
Molecular Formula:C14H14 O7
Molecular Weight:294.2568
Hs Code.:
DSSTox Substance ID:DTXSID30910986
Nikkaji Number:J91.123B

Synonyms:BRN 0289008;beta-(Hydroxymethoxy)tricarballylic acid gamma-lactone benzyl ester;109100-88-1;Tricarballylic acid, beta-(hydroxymethoxy)-, gamma-lactone, benzyl ester;DTXSID30910986;YA437700;LS-156983;{4-[2-(BENZYLOXY)-2-OXOETHYL]-5-OXO-1,3-DIOXOLAN-4-YL}ACETIC ACID

Suppliers and Price of beta-(Hydroxymethoxy)tricarballylic acid gamma-lactone benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of beta-(Hydroxymethoxy)tricarballylic acid gamma-lactone benzyl ester

Chemical Property:

Vapor Pressure:8.94E-11mmHg at 25°C
Boiling Point:499°Cat760mmHg
Flash Point:189.3°C
Density:1.361g/cm³
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:294.07395278
Heavy Atom Count:21
Complexity:414

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1OC(=O)C(O1)(CC(=O)O)CC(=O)OCC2=CC=CC=C2

Technology Process of beta-(Hydroxymethoxy)tricarballylic acid gamma-lactone benzyl ester

There total 3 articles about beta-(Hydroxymethoxy)tricarballylic acid gamma-lactone benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 4767-12-8
4,4-(5-oxo-1,3-dioxolane)diacetic acid anhydride

: 100-51-6,185532-71-2
benzyl alcohol

: 109100-88-1
2-<4-<(benzyloxycarbonyl)methyl>-5-oxo-1,3-dioxolan-4-yl>acetic acid

Guidance literature:: With pyridine; In chloroform; for 24h; Heating;
DOI:10.1248/cpb.47.1284

Reference yield:

: 144-16-1
5-oxo-1,3-dioxolan-4-ylidenedi(acetic acid)

: 109100-88-1
2-<4-<(benzyloxycarbonyl)methyl>-5-oxo-1,3-dioxolan-4-yl>acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / POCl₃; N,N-dimethylaniline / CHCl₃ / 20 °C

2: 81 percent / pyridine / CHCl₃ / 24 h / Heating

With pyridine; N,N-dimethyl-aniline; trichlorophosphate; In chloroform; 1: Dehydration / 2: Esterification;
DOI:10.1248/cpb.47.1284

Reference yield:

: 77-92-9,906507-37-7
citric acid

: 109100-88-1
2-<4-<(benzyloxycarbonyl)methyl>-5-oxo-1,3-dioxolan-4-yl>acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 46 percent / 0.5 h / 160 °C

2: 61 percent / POCl₃; N,N-dimethylaniline / CHCl₃ / 20 °C

3: 81 percent / pyridine / CHCl₃ / 24 h / Heating

With pyridine; N,N-dimethyl-aniline; trichlorophosphate; In chloroform; 1: Condensation / 2: Dehydration / 3: Esterification;
DOI:10.1248/cpb.47.1284