N-(6-Methyl-2-pyridinyl)-N'-phenylurea

Base Information

• Chemical Name: N-(6-Methyl-2-pyridinyl)-N'-phenylurea
• CAS No.: 91597-29-4
• Molecular Formula: C₁₃H₁₃N₃O
• Molecular Weight: 227.266
• Hs Code.: 2933399090
• European Community (EC) Number: 688-727-5
• NSC Number: 204137
• UNII: 66IP83KR8D
• DSSTox Substance ID: DTXSID20238641
• Nikkaji Number: J3.494.126B
• Wikidata: Q83120930
• ChEMBL ID: CHEMBL1480891
• Mol file: 91597-29-4.mol

Synonyms:N-(6-Methyl-2-pyridinyl)-N'-phenylurea;91597-29-4;1-(6-methylpyridin-2-yl)-3-phenylurea;66IP83KR8D;NSC204137;NSC 204137;UNII-66IP83KR8D;NSC-204137;1-(6-Methyl-2-pyridyl)-3-phenylurea;3-(6-methylpyridin-2-yl)-1-phenylurea;Oprea1_313527;Oprea1_615926;MLS001181881;SCHEMBL1142765;CHEMBL1480891;DTXSID20238641;IGCMIVVIDBZYRE-UHFFFAOYSA-N;HMS2863P15;AKOS000546057;CCG-128197;1-(6-methyl-2-pyridyl)-3-phenyl-urea;NCGC00246637-01;SMR000567546;N-(6-Methyl-2-pyridinyl)-N'-phenylurea #;Urea, N-(6-methyl-2-pyridinyl)-N'-phenyl-;AG-389/30939058;Z56261368

Chemical Property of N-(6-Methyl-2-pyridinyl)-N'-phenylurea

Chemical Property:

• Vapor Pressure: 0.0025mmHg at 25°C
• Boiling Point: 287.3°Cat760mmHg
• Flash Point: 127.6°C
• PSA: 54.02000
• Density: 1.267g/cm³
• LogP: 3.18000
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 227.105862047
• Heavy Atom Count: 17
• Complexity: 251

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=NC(=CC=C1)NC(=O)NC2=CC=CC=C2

Technology Process of N-(6-Methyl-2-pyridinyl)-N'-phenylurea

There total 6 articles about N-(6-Methyl-2-pyridinyl)-N'-phenylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

α-picoline (109-06-8) → N-(6-methyl-[2]pyridyl)-N'-phenyl-urea (91597-29-4)

Guidance literature:

Multi-step reaction with 3 steps

1: NaNH₂; xylene

3: lead (II)-acetate; aq.-ethanolic NaOH

With sodium hydroxide; lead acetate; sodium amide; xylene;

DOI:10.1002/ardp.19362740707

Reference yield:

2-Amino-6-methylpyridine (1824-81-3) → N-(6-methyl-[2]pyridyl)-N'-phenyl-urea (91597-29-4)

Guidance literature:

Multi-step reaction with 2 steps

2: lead (II)-acetate; aq.-ethanolic NaOH

With sodium hydroxide; lead acetate;

DOI:10.1002/ardp.19362740707

Reference yield:

N-(3-methylpyridin-2-yl)-N'-phenyl-thiourea (53385-83-4) → N-(6-methyl-[2]pyridyl)-N'-phenyl-urea (91597-29-4)

Guidance literature:

With sodium hydroxide; lead acetate;

DOI:10.1002/ardp.19362740707

upstream raw materials:

(6-methyl-pyridin-2-yl)-carbamic acid ethyl ester

aniline

N-(3-methylpyridin-2-yl)-N'-phenyl-thiourea

2-Amino-6-methylpyridine