2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile

Base Information

Chemical Name:2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile
CAS No.:39515-47-4
Deprecated CAS:52315-06-7,66775-58-4
Molecular Formula:C14H11NO2
Molecular Weight:225.247
Hs Code.:2926909090
European Community (EC) Number:257-841-3,254-486-6
DSSTox Substance ID:DTXSID00885773
Nikkaji Number:J43.143E,J274.182B
Wikidata:Q82864459
Mol file:39515-47-4.mol

Synonyms:alpha-hydroxy-3-phenoxybenzeneacetonitrile;HPBAN cpd;hydroxy-3-phenoxybenzeneacetonitrile

Suppliers and Price of 2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
α-Hydroxy-3-phenoxybenzeneacetonitrile(>90%)
500mg
$ 125.00

Matrix Scientific
2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile 97%
100g
$ 2160.00

Matrix Scientific
2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile 97%
25g
$ 864.00

Crysdot
2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile 95+%
25g
$ 454.00

Chemenu
2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile 95%
25g
$ 428.00

Ambeed
2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile 97%containinglessthan10%EA
1g
$ 175.00

Ambeed
2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile 97%containinglessthan10%EA
100mg
$ 39.00

Alichem
2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile
25g
$ 866.00

Alichem
2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile
5g
$ 291.89

Total 22 raw suppliers

Chemical Property of 2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile

Chemical Property:

Appearance/Colour:clear orange solution
Melting Point:79℃ (ethanol )
Boiling Point:399.8 °C at 760 mmHg
PKA:10.33±0.20(Predicted)
Flash Point:195.6 °C
PSA：53.25000
Density:1.22 g/cm³
LogP:3.03588
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
Solubility.:Chloroform, DMSO
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:225.078978594
Heavy Atom Count:17
Complexity:277

Purity/Quality:

97% ^*data from raw suppliers

α-Hydroxy-3-phenoxybenzeneacetonitrile(>90%) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)OC2=CC=CC(=C2)C(C#N)O
Uses α-Hydroxy-3-phenoxybenzeneacetonitrile is an intermediate in synthesizing τ-Fluvalinate (F601100), a synthetic pyrethroid aracacide. τ-Fluvalinate is commonly used to control Varroa jacobsoni (a parasitic mite) in honey bee colonies.

Technology Process of 2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile

There total 47 articles about 2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 74-90-8
hydrogen cyanide

: 39515-51-0
3-Phenoxybenzaldehyde

: 39515-47-4,52315-06-7,61826-76-4,71962-66-8
(S)-m-phenoxybenzaldehyde cyanohydrin

Guidance literature:: With hydroxynitrile lyase from Hevea brasiliensis; In water; at 15 ℃; for 0.25h; pH 5.5;
DOI:10.1016/S0040-4020(98)00901-6

Reference yield: 92.0%

: 113301-28-3
O-acetyl-(S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile

: 39515-47-4,52315-06-7,61826-76-4,71962-66-8
(S)-m-phenoxybenzaldehyde cyanohydrin

Guidance literature:: With ethanol; In di-isopropyl ether; at 25 ℃; for 6h; lipase from Pseudomonas cepacia (Amano);
DOI:10.1021/jo00047a016

Reference yield: 85.0%

: 120838-94-0
(R,S)-cyano(3-phenoxyphenyl)methyl butyrate

: 39515-47-4,52315-06-7,61826-76-4,71962-66-8
(S)-m-phenoxybenzaldehyde cyanohydrin

: (R)-cyano(3-phenoxyphenyl)methyl butanoate

Guidance literature:: With Pseudomonas cepacia lipase immobilised in a gelatin matrix; butan-1-ol; In hexane; for 8h;
DOI:10.1016/S0957-4166(00)00303-7