4-Benzyloxy-3-methoxycinnamic acid

Base Information

Chemical Name:4-Benzyloxy-3-methoxycinnamic acid
CAS No.:7152-95-6
Molecular Formula:C₁₇H₁₆O₄
Molecular Weight:284.312
Hs Code.:2918990090
European Community (EC) Number:636-120-0
Nikkaji Number:J1.086.999D,J2.242.808J
Wikidata:Q76310810
Mol file:7152-95-6.mol

Synonyms:7152-95-6;4-BENZYLOXY-3-METHOXYCINNAMIC ACID;3-(4-(Benzyloxy)-3-methoxyphenyl)acrylic acid;3-[4-(benzyloxy)-3-methoxyphenyl]acrylic acid;(E)-3-(4-(benzyloxy)-3-methoxyphenyl)acrylic acid;(2E)-3-[4-(benzyloxy)-3-methoxyphenyl]prop-2-enoic acid;SCHEMBL1608802;WSOBQOYHYGVEIR-CSKARUKUSA-N;STR04898;STL573060;AKOS000304703;3-Methoxy-4-(benzyloxy)benzeneacrylic acid;CS-0226834;3-(4-(Benzyloxy)-3-methoxyphenyl)acrylicacid;A837231;J-511471;(E)-3-(4-benzyloxy-3-methoxy-phenyl)prop-2-enoate

Suppliers and Price of 4-Benzyloxy-3-methoxycinnamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
4-BENZYLOXY-3-METHOXYCINNAMIC ACID Aldrich
50mg
$ 144.00

Crysdot
3-(4-(Benzyloxy)-3-methoxyphenyl)acrylicacid 95+%
100g
$ 474.00

American Custom Chemicals Corporation
3-[4-(BENZYLOXY)-3-METHOXYPHENYL]ACRYLIC ACID 95.00%
5G
$ 913.21

American Custom Chemicals Corporation
3-[4-(BENZYLOXY)-3-METHOXYPHENYL]ACRYLIC ACID 95.00%
1G
$ 633.91

Alfa Aesar
4-Benzyloxy-3-methoxycinnamic acid, 98%
5g
$ 89.90

Alfa Aesar
4-Benzyloxy-3-methoxycinnamic acid, 98%
1g
$ 20.20

AK Scientific
3-[4-(Benzyloxy)-3-methoxyphenyl]acrylicacid
1g
$ 91.00

AHH
4-BENZYLOXY-3-METHOXYCINNAMIC ACID 98%
25g
$ 360.00

Total 19 raw suppliers

Chemical Property of 4-Benzyloxy-3-methoxycinnamic acid

Chemical Property:

Vapor Pressure:1.2E-09mmHg at 25°C
Melting Point:188oC
Boiling Point:470.3°Cat760mmHg
Flash Point:173.2°C
PSA：55.76000
Density:1.216g/cm³
LogP:3.37200
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:284.10485899
Heavy Atom Count:21
Complexity:347

Purity/Quality:

97% ^*data from raw suppliers

4-BENZYLOXY-3-METHOXYCINNAMIC ACID Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)C=CC(=O)O)OCC2=CC=CC=C2
Isomeric SMILES:COC1=C(C=CC(=C1)/C=C/C(=O)O)OCC2=CC=CC=C2

Technology Process of 4-Benzyloxy-3-methoxycinnamic acid

There total 7 articles about 4-Benzyloxy-3-methoxycinnamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 2426-87-1
3-methoxy-4-(phenylmethoxy)benzaldehyde

: 141-82-2
malonic acid

: 77795-22-3,7152-95-6
4-benzyloxy-3-methoxycinnamic acid

Guidance literature:: 3-methoxy-4-(phenylmethoxy)benzaldehyde; malonic acid; With piperidine; pyridine; at 90 ℃; Reflux;

With water; for 1h; Cooling with ice;
DOI:10.1021/jf8006536

Reference yield: 86.0%

: 481701-70-6
benzyl 3-methoxy-4-benzyloxycinnamate

: 77795-22-3,7152-95-6
4-benzyloxy-3-methoxycinnamic acid

Guidance literature:: With potassium hydroxide; In ethanol; water; for 2h; Reflux;
DOI:10.1007/s11746-011-1889-6

Reference yield:

: 1135-24-6,537-98-4
3-(4-hydroxy-3-methoxyphenyl)acrylic acid

: 77795-22-3,7152-95-6
4-benzyloxy-3-methoxycinnamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 15 h / Inert atmosphere

2: potassium hydroxide / ethanol; water / 2 h / Reflux

With potassium carbonate; potassium hydroxide; In ethanol; water; N,N-dimethyl-formamide;
DOI:10.1007/s11746-011-1889-6