Chemical Property of Conduritol b epoxide
Chemical Property:
- Appearance/Colour:white crystalline solid
- Vapor Pressure:0mmHg at 25°C
- Melting Point:157-159 °C
- Refractive Index:1.732
- Boiling Point:360.478 °C at 760 mmHg
- PKA:13.08±0.70(Predicted)
- Flash Point:171.811 °C
- PSA：93.45000
- Density:1.926 g/cm3
- LogP:-2.78900
- Storage Temp.:2-8°C
- Solubility.:Soluble in Water (up to 25 mg/ml) or in DMSO
- XLogP3:-2.7
- Hydrogen Bond Donor Count:4
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:0
- Exact Mass:162.05282342
- Heavy Atom Count:11
- Complexity:154
- Purity/Quality:
-
99%, *data from raw suppliers
Conduritol B epoxide *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:C1(C(C(C2C(C1O)O2)O)O)O
- Isomeric SMILES:[C@@H]1([C@@H]([C@H]([C@H]2[C@@H]([C@@H]1O)O2)O)O)O
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Description
Conduritol B epoxide (6090-95-5) is a β-Glycosidase inhibitor.1,2 May be used for generation of the “Gaucher mouse”3 and the in vitro model of the Gaucher cell4.
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Uses
Conduritol B Epoxide acts on b-glucosidases from widely differing sources to show a loss of enzymic activity: from various Aspergillus species, yeast, snail, sweet almonds, and mammals. The other enzymes that have been found to be covalently inhibited are a- glucosidase from yeast and the sucrase-isomaltase complex from rabbit small intestine. inhibitor of glucosidases
