3-Ethoxy-2-methyl-3-oxopropanoic acid

Base Information

Chemical Name:3-Ethoxy-2-methyl-3-oxopropanoic acid
CAS No.:2985-33-3
Molecular Formula:C6H10O4
Molecular Weight:146.143
Hs Code.:2918990090
NSC Number:165647
DSSTox Substance ID:DTXSID80304412
Nikkaji Number:J1.653.714D
Mol file:2985-33-3.mol

Synonyms:3-ethoxy-2-methyl-3-oxopropanoic acid;2985-33-3;2-Methyl-malonic acid monoethyl ester;methylmalonic acid monoethyl ester;ethyl 2-carboxypropionate;NSC165647;SCHEMBL358989;2-(ethoxycarbonyl)propanoic acid;DTXSID80304412;REGOCDRDNZNRMC-UHFFFAOYSA-N;methyl-malonic acid monoethyl ester;CAA98533;MFCD02684780;3-ethoxy-2-methyl-3-oxopropanoicacid;AKOS006277480;NSC-165647;SB36452;BS-49724;BB 0261898;CS-0135406;EN300-98004;C91037

Suppliers and Price of 3-Ethoxy-2-methyl-3-oxopropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 25 raw suppliers

Chemical Property of 3-Ethoxy-2-methyl-3-oxopropanoic acid

Chemical Property:

Vapor Pressure:0.0112mmHg at 25°C
Refractive Index:1.438
Boiling Point:242.45 °C at 760 mmHg
Flash Point:98.414 °C
PSA：63.60000
Density:1.159 g/cm³
LogP:0.27020
Storage Temp.:2-8°C
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:146.05790880
Heavy Atom Count:10
Complexity:141

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C)C(=O)O
Uses Ethyl 2-Carboxypropionate is a useful synthetic compound.

Technology Process of 3-Ethoxy-2-methyl-3-oxopropanoic acid

There total 16 articles about 3-Ethoxy-2-methyl-3-oxopropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 609-08-5
Diethyl methylmalonate

: 2985-33-3
monoethyl methylmalonate

Guidance literature:: With potassium hydroxide; In ethanol; at 0 - 20 ℃; for 2h;
DOI:10.1038/ja.2012.124

Reference yield: 96.0%

: 103362-70-5
potassium ethyl methylmalonate

: 2985-33-3
monoethyl methylmalonate

Guidance literature:: With hydrogenchloride; In water; at -10 ℃;
DOI:10.1016/S0008-6215(82)80018-9

Reference yield: 73.0%

: 1447797-53-6
diethyl 2-methyl-2-(4-(trifluoromethyl)benzyl)malonate

: 2985-33-3
monoethyl methylmalonate

Guidance literature:: diethyl 2-methyl-2-(4-(trifluoromethyl)benzyl)malonate; With N¹,N¹,N¹²,N¹²-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a:2,1'-c][1,4]diazepine-2,12-diamine; In N,N-dimethyl-formamide; at 20 ℃; for 72h; Inert atmosphere; Glovebox; UV-irradiation;

With hydrogenchloride; In water; at 0 ℃; pH=< 3; chemoselective reaction; Inert atmosphere;
DOI:10.1021/ja4050168