Methyl 4-{[2-(5-chloro-2-fluorophenyl)-5-methoxypyrimidin-4-yl]amino}nicotinate

Base Information

• Chemical Name: Methyl 4-{[2-(5-chloro-2-fluorophenyl)-5-methoxypyrimidin-4-yl]amino}nicotinate
• CAS No.: 674793-50-1
• Molecular Formula: C18H14ClFN4O3
• Molecular Weight: 388.78
• Mol file: 674793-50-1.mol

Synonyms:

Chemical Property of Methyl 4-{[2-(5-chloro-2-fluorophenyl)-5-methoxypyrimidin-4-yl]amino}nicotinate

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

Methyl 4-{[2-(5-chloro-2-fluorophenyl)-5-methoxypyrimidin-4-yl]amino}nicotinate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl 4-{[2-(5-chloro-2-fluorophenyl)-5-methoxypyrimidin-4-yl]amino}nicotinate

There total 1 articles about Methyl 4-{[2-(5-chloro-2-fluorophenyl)-5-methoxypyrimidin-4-yl]amino}nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

C11H7Cl2FN2O (674793-47-6) + methyl 4-aminonicotinate (16135-36-7) → C18H14ClFN4O3 (674793-50-1)

Guidance literature:

With racemic-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl; caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; at 95 ℃; for 18h;

upstream raw materials:

C₁₁H₇Cl₂FN₂O

methyl 4-aminonicotinate